(Q43127109)

English

Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery

scientific article published on 4 November 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery (English)

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

1 reference

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author name string

Tatiana F González-Cestari

1

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Brandon J Henderson

2

1 reference

Europe PubMed Central

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14 November 2017

Ryan E Pavlovicz

3

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Susan B McKay

4

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Raed A El-Hajj

5

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Aravinda B Pulipaka

6

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Crina M Orac

7

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Damon D Reed

8

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

R Thomas Boyd

9

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Michael X Zhu

10

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Chenglong Li

11

1 reference

Europe PubMed Central

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14 November 2017

Stephen C Bergmeier

12

1 reference

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14 November 2017

Dennis B McKay

13

1 reference

Europe PubMed Central

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14 November 2017

language of work or name

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publication date

4 November 2008

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Europe PubMed Central

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14 November 2017

Journal of Pharmacology and Experimental Therapeutics

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Europe PubMed Central

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14 November 2017

328

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Europe PubMed Central

PMC publication ID

14 November 2017

2

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

504-515

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

Pharmacological and immunological identification of native alpha7 nicotinic receptors: evidence for homomeric and heteromeric alpha7 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Acetylcholine nicotinic receptors: finding the putative binding site of allosteric modulators using the "blind docking" approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Structure activity studies of ring E analogues of methyllycaconitine. Part 2: Synthesis of antagonists to the alpha3beta4* nicotinic acetylcholine receptors through modifications to the ester

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

A structural model of agonist binding to the α3β4 neuronal nicotinic receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Pharmacological characterization of recombinant bovine alpha3beta4 neuronal nicotinic receptors stably expressed in HEK 293 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Desensitization of neuronal nicotinic receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Characterization of human alpha4beta2 neuronal nicotinic receptors stably expressed in SH-EP1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Competitive neuronal nicotinic receptor antagonists: a new direction for drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Characterization of the recombinant human neuronal nicotinic acetylcholine receptors alpha3beta2 and alpha4beta2 stably expressed in HEK293 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Neuronal nicotinic acetylcholine receptors as novel drug targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Rat alpha3/beta4 subtype of neuronal nicotinic acetylcholine receptor stably expressed in a transfected cell line: pharmacology of ligand binding and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

alpha 5 Subunit alters desensitization, pharmacology, Ca++ permeability and Ca++ modulation of human neuronal alpha 3 nicotinic receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Characterization of human recombinant neuronal nicotinic acetylcholine receptor subunit combinations alpha2beta4, alpha3beta4 and alpha4beta4 stably expressed in HEK293 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Neuronal nicotinic acetylcholine receptors on bovine chromaffin cells: cloning, expression, and genomic organization of receptor subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Electrophysiological and biochemical studies on enhancement of desensitization by phenothiazine neuroleptics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Calcium channel effectors are potent non-competitive blockers of acetylcholine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Effect of Noncompetitive Nicotinic Receptor Blockers on Catecholamine Release from Cultured Adrenal Chromaffin Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

Studies on the effect of histrionicotoxin on the monocellular electroplax from Electrophorus electricus and on the binding of (3H)acetylcholine to membrane fragments from Torpedo marmorata

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

25 May 2018

The synthesis of 5-substituted ring E analogs of methyllycaconitine via the Suzuki-Miyaura cross-coupling reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

15 August 2018

Analogs of methyllycaconitine as novel noncompetitive inhibitors of nicotinic receptors: pharmacological characterization, computational modeling, and pharmacophore development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

15 August 2018

Allosteric binding sites on muscarinic acetylcholine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

15 August 2018

The relaxed complex method: Accommodating receptor flexibility for drug design with an improved scoring scheme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

15 August 2018

Galantamine blocks delayed rectifier, but not transient outward potassium current in rat dissociated hippocampal pyramidal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

15 August 2018

Structure-activity studies with ring E analogues of methyllycaconitine on bovine adrenal alpha3beta4* nicotinic receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

15 August 2018

Evidence for spare nicotinic acetylcholine receptors and a beta 4 subunit in bovine adrenal chromaffin cells: studies using bromoacetylcholine, epibatidine, cytisine and mAb35.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

15 August 2018

Local anesthetics and histrionicotoxin are allosteric inhibitors of the acetylcholine receptor. Studies of clonal muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682284

15 August 2018

Selective inhibition of cholinergic receptor-mediated 45Ca++ uptake and catecholamine secretion from adrenal chromaffin cells by taxol and vinblastine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18984653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of microtubule-active agents with nicotinic acetylcholine receptors. Relationship to their inhibition of catecholamine secretion by adrenal chromaffin cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18984653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of noncompetitive inhibitors with the acetylcholine receptor. The site specificity and spectroscopic properties of ethidium binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/18984653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic and nonnicotinic receptor-mediated actions of vinblastine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18984653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nicotinic acetylcholine receptor of the bovine chromaffin cell, a new target for dihydropyridines

1 reference

https://pubmed.ncbi.nlm.nih.gov/18984653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ring E analogs of methyllycaconitine (MLA) as novel nicotinic antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/18984653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-type calcium channel ligands block nicotine-induced signaling to CREB by inhibiting nicotinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18984653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of Ca2+-activated K+ channels by galantamine can also contribute to the potentiation of catecholamine secretion from chromaffin cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18984653

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/JPET.108.144576

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 November 2017

ResearchGate publication ID

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