(Q43128475)

English

O(6)-Methylguanine DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression is correlated with progression-free survival in patients with glioblastoma

scientific article published on 16 March 2010

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

O(6)-Methylguanine DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression is correlated with progression-free survival in patients with glioblastoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

hypermethylation

1 reference

based on heuristic

inferred from title

immunohistochemistry

1 reference

based on heuristic

inferred from title

Yukihiko Sonoda

1

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

author name string

Michiko Yokosawa

2

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Ryuta Saito

3

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Masayuki Kanamori

4

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Yoji Yamashita

5

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Toshihiro Kumabe

6

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Mika Watanabe

7

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Teiji Tominaga

8

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

publication date

16 March 2010

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

International Journal of Clinical Oncology

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

352-358

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

https://scigraph.springernature.com/pub.10.1007/s10147-010-0065-6

0 references

Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene

1 reference

https://api.crossref.org/works/10.1007%2FS10147-010-0065-6

21 January 2018

Long-term survival with glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

O6-methyl-guanine-DNA methyltransferase methylation in serum and tumor DNA predicts response to 1,3-bis(2-chloroethyl)-1-nitrosourea but not to temozolamide plus cisplatin in glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of O6-methylguanine-DNA methyltransferase determined by promoter hypermethylation and immunohistochemical expression in anaplastic gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterogeneity in the expression of markers for drug resistance in brain tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between O6-methylguanine-DNA methyltransferase and survival in inoperable newly diagnosed glioblastoma patients treated with neoadjuvant temozolomide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resection, biopsy, and survival in malignant glial neoplasms. A retrospective study of clinical parameters, therapy, and outcome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of sex and the presence of giant cells on postoperative long-term survival in adult patients with supratentorial glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ten-year survival among patients with supratentorial astrocytomas grade III and IV

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between expression of O6-methylguanine-DNA methyltransferase, glutathione-S-transferase π in glioblastoma and the survival of the patients treated with nimustine hydrochloride: An immunohistochemical analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: proposal of a feasible immunohistochemical approach.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glioblastoma Multiforme: A Clinical Survey

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MGMT immunohistochemical expression and promoter methylation in human glioblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term survival in patients with glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MS-MLPA: an attractive alternative laboratory assay for robust, reliable, and semiquantitative detection of MGMT promoter hypermethylation in gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term survivors of glioblastoma: clinical features and molecular analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term survival in patients with supratentorial glioblastoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

O6-methylguanine-DNA methyltransferase methylation and TP53 mutation in malignant astrocytomas and their relationships with clinical course

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Which glioblastoma multiforme patient will become a long-term survivor? A population-based study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between promoter hypermethylation of the O6-methylguanine-deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inter- and intracellular heterogeneity of O6-alkylguanine-DNA alkyltransferase expression in human brain tumors: possible significance in nitrosourea therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MGMT prognostic impact on glioblastoma is dependent on therapeutic modalities.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of the immunohistochemical expression of O6-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MGMT gene silencing and benefit from temozolomide in glioblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MGMT promoter hypermethylation in a series of 104 glioblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of clinical features and methylation status of MGMT gene promoter in glioblastomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical study for O6-methylguanine-DNA methyltransferase in the non-neoplastic and neoplastic components of gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/20232102

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10147-010-0065-6

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43128475&oldid=2166161294"