(Q43132731)

14 November 2017

1 reference

title

The structure of IL2 bound to the three chains of the IL2 receptor and how signaling occurs (English)

1 reference

14 November 2017

Kendall A Smith

1

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14 November 2017

14 August 2006

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14 November 2017

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14 November 2017

5

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14 November 2017

3

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Creative Commons Attribution 2.0 Generic

14 November 2017

start time

14 August 2006

1 reference

April 2022 Public Data File from Crossref

Creative Commons Attribution 2.0 Generic

0 references

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

exact match

https://scigraph.springernature.com/pub.10.1186/1476-9433-5-3

0 references

cites work

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25 May 2018

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25 May 2018

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Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor

25 May 2018

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25 May 2018

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Stat5a/b are essential for normal lymphoid development and differentiation

25 May 2018

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Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors

25 May 2018

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The quantal theory of how the immune system discriminates between "self and non-self"

25 May 2018

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A permissive role for phosphatidylinositol 3-kinase in the Stat5-mediated expression of cyclin D2 by the interleukin-2 receptor

25 May 2018

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Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex

25 May 2018

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Biosensor analysis of the interleukin-2 receptor complex

25 May 2018

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Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells

25 May 2018

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Solution assembly of the pseudo-high affinity and intermediate affinity interleukin-2 receptor complexes

25 May 2018

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Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

25 May 2018

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Expression and ligand binding characterization of the beta-subunit (p75) ectodomain of the interleukin-2 receptor

25 May 2018

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Soluble IL-2 receptor beta and gamma subunits: ligand binding and cooperativity

25 May 2018

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Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

25 May 2018

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Solution Assembly of a Soluble, Heteromeric, High Affinity Interleukin-2 Receptor Complex

25 May 2018

1 reference

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Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation.

25 May 2018

1 reference

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The common gamma-chain for multiple cytokine receptors.

25 May 2018

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T cell growth factor receptors. Quantitation, specificity, and biological relevance

25 May 2018

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The interleukin 2 receptor. Functional consequences of its bimolecular structure

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

Contribution of a p75 interleukin 2 binding peptide to a high-affinity interleukin 2 receptor complex

25 May 2018

1 reference

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Interleukin 2 high-affinity receptor expression requires two distinct binding proteins

25 May 2018

1 reference

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Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions

25 May 2018

1 reference

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Interleukin 2 regulates its own receptors

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

Crystallization and preliminary X-ray diffraction studies of a complex between interleukin-2 and a soluble form of the p55 component of the high affinity interleukin-2 receptor.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

The interleukin 2 receptor

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

Interleukin-2-triggered Raf-1 expression, phosphorylation, and associated kinase activity increase through G1 and S in CD3-stimulated primary human T cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

An associated molecule, p64, with IL-2 receptor beta chain. Its possible involvement in the formation of the functional intermediate-affinity IL-2 receptor complex

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

The interleukin-2 T-cell system: a new cell growth model.

25 May 2018

1 reference

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Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

16 June 2018

1 reference

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Compensatory energetic mechanisms mediating the assembly of signaling complexes between interleukin-2 and its alpha, beta, and gamma(c) receptors

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

Heterogeneity of human T-cell growth factor(s) due to variable glycosylation.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

On the Physiology of the Salivary Secretion: Part II. On the Mutual Antagonism of Atropin and Pilocarpin, having especial reference to their relations in the Sub-maxillary Gland of the Cat

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1562422

Analysis of the role of the interleukin-2 receptor gamma chain in ligand binding

1 December 2018

1 reference

12 December 2020

Ligand Binding Analysis of Soluble Interleukin-2 Receptor Complexes by Surface Plasmon Resonance

1 reference

12 December 2020

A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor

1 reference

12 December 2020

The structure of interleukin-2 complexed with its alpha receptor

1 reference

12 December 2020

Production and characterization of monoclonal antibodies to human interleukin 2: strategy and tactics

1 reference

12 December 2020

Unraveling the structure of IL-2

1 reference

12 December 2020

Identifiers

DOI

10.1186/1476-9433-5-3

1 reference

PMC publication ID

1562422

Dimensions Publication ID

14 November 2017

0 references

1 reference

PMC publication ID

1562422

14 November 2017

PubMed publication ID

16907989

1 reference

PMC publication ID

1562422