(Q38518751)

3 September 2017

title

A permissive role for phosphatidylinositol 3-kinase in the Stat5-mediated expression of cyclin D2 by the interleukin-2 receptor (English)

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3 September 2017

Brad H Nelson

5

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author name string

James J Moon

1

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3 September 2017

Eric D Rubio

2

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3 September 2017

Anthony Martino

3

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3 September 2017

Anton Krumm

4

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3 September 2017

language of work or name

English

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publication date

2 December 2003

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Journal of Biological Chemistry

3 September 2017

published in

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3 September 2017

volume

279

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3 September 2017

issue

7

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3 September 2017

page(s)

5520-5527

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CDK inhibitors: positive and negative regulators of G1-phase progression

3 September 2017

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Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

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Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity

21 January 2018

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The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.

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Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

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Phosphatidylinositol 3-kinase potentiates, but does not trigger, T cell proliferation mediated by the IL-2 receptor

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

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Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase.

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Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

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Growth hormone- and prolactin-induced proliferation of insulinoma cells, INS-1, depends on activation of STAT5 (signal transducer and activator of transcription 5).

21 January 2018

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Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2.

21 January 2018

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Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors

21 January 2018

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Phosphatidylinositol 3-kinase c2alpha contains a nuclear localization sequence and associates with nuclear speckles

21 January 2018

1 reference

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Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F

21 January 2018

1 reference

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Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells

21 January 2018

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Functionally distinct isoforms of STAT5 are generated by protein processing

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M308998200

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3 September 2017

1 reference