(Q24290689)

phosphatidylinositol 3-kinase regulator activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

2

K J Hurt

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Solomon Halbert Snyder

9

object named as

S H Snyder

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author name string

K Ye

1

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F Y Wu

3

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M Fang

4

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H R Luo

5

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J J Hong

6

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S Blackshaw

7

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C D Ferris

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

8

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language of work or name

English

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publication date

8 December 2000

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published in

Cell

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volume

103

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page(s)

919-30

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issue

6

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Src, ras, and rac mediate the migratory response elicited by NGF and PMA in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Neurite outgrowth in PC12 cells deficient in GAP-43

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Developmental expression pattern of phototransduction components in mammalian pineal implies a light-sensing function.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Intact Ras function is required for sustained activation and nuclear translocation of extracellular signal-regulated kinases in nerve growth factor-stimulated PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Oncogenes and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Biological and biochemical properties of human rasH genes mutated at codon 61.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Multiple ras effector pathways contribute to G(1) cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3-OH kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Construction of retroviral vectors with improved safety, gene expression, and versatility.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Phosphoinositide 3-kinase in rat liver nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Human-specific nuclear protein that associates with the polar region of the mitotic apparatus: distribution in a human/hamster hybrid cell

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Recent insights in phosphatidylinositol signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Phosphatidylinositol 3-Kinase in HL-60 Nuclei Is Bound to the Nuclear Matrix and Increases During Granulocytic Differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Nuclear cotransport mechanism of cytoplasmic human MxB protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

The basic science of gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Increase in nuclear phosphatidylinositol 3-kinase activity and phosphatidylinositol (3,4,5) trisphosphate synthesis precede PKC-zeta translocation to the nucleus of NGF-treated PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Redistribution of the nuclear mitotic apparatus protein (NuMA) during mitosis and nuclear assembly. Properties of purified NuMA protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Activation of phosphatidylinositol 3-kinase by insulin

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

The small nuclear GTPase Ran: how much does it run?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

The activation and nuclear translocation of extracellular signal-regulated kinases (ERK-1 and -2) appear not to be required for elongation of neurites in PC12D cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Evidence that a phosphatidylinositol 3,4,5-trisphosphate-binding protein can function in nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Subcellular distribution in cerebral cortex of two proteins phosphorylated by a cAMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Mammalian Ras interacts directly with the serine/threonine kinase Raf

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Ligation of CD28 receptor by B7 induces formation of D-3 phosphoinositides in T lymphocytes independently of T cell receptor/CD3 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Role of cyclins in neuronal differentiation of immortalized hippocampal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

The nuclear-mitotic apparatus protein is important in the establishment and maintenance of the bipolar mitotic spindle apparatus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Nerve growth factor in the nucleus: interaction with receptors on the nuclear membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021

Structural basis for the binding of proline-rich peptides to SH3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900195-1

7 January 2021