(Q43151764)

14 November 2017

mGluR4 positive allosteric modulators with potential for the treatment of Parkinson's disease: WO09010455. (English)

1 reference

14 November 2017

1 reference

Stephen P East

1

1 reference

PubMed ID

20180624

14 November 2017

Kai Gerlach

series ordinal

2

1 reference

PubMed ID

20180624

14 November 2017

language of work or name

English

0 references

publication date

1 March 2010

1 reference

Expert Opinion on Therapeutic Patents

14 November 2017

1 reference

14 November 2017

20

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14 November 2017

3

1 reference

14 November 2017

441-445

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Dopamine: 50 years in perspective

14 November 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Therapeutic potential of group III metabotropic glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Metabotropic glutamate receptors in the basal ganglia motor circuit

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

mGluR4-positive allosteric modulation as potential treatment for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-lead

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

Discovery of molecular switches that modulate modes of metabotropic glutamate receptor subtype 5 (mGlu5) pharmacology in vitro and in vivo within a series of functionalized, regioisomeric 2- and 5-(phenylethynyl)pyrimidines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543770903551295

10.1517/13543770903551295

21 January 2018

Identifiers

DOI

1 reference

14 November 2017

1 reference

PubMed ID

20180624