(Q43152968)

English

Utility of multivariate analysis in support of in vitro metabolite identification studies: retrospective analysis using the antidepressant drug nefazodone

scientific article published in April 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Utility of multivariate analysis in support of in vitro metabolite identification studies: retrospective analysis using the antidepressant drug nefazodone (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

multivariate statistics

1 reference

based on heuristic

inferred from title

metabolite identification

1 reference

based on heuristic

inferred from title

object named as

metabolite identification

4 February 2023

author name string

R P Schneider

1

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

H Zhang

2

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

L Mu

3

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

A S Kalgutkar

4

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

R Bonner

5

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

language of work or name

0 references

publication date

1 April 2010

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

40

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

262-274

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

Approaches to the assessment of stable and chemically reactive drug metabolites in early clinical trials

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Comparison of the bioactivation potential of the antidepressant and hepatotoxin nefazodone with aripiprazole, a structural analog and marketed drug

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: From extraction to data analysis

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Assessment of three human in vitro systems in the generation of major human excretory and circulating metabolites

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Multivariate approaches for efficient detection of potential metabolites from liquid chromatography/mass spectrometry data

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Dimensionality reduction and visualization in principal component analysis

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

A high-capacity LC/MS system for the bioanalysis of samples generated from plate-based metabolic screening

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Bioactivation of the nontricyclic antidepressant nefazodone to a reactive quinone-imine species in human liver microsomes and recombinant cytochrome P450 3A4.

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Efficient mining of myxobacterial metabolite profiles enabled by liquid chromatography-electrospray ionisation-time-of-flight mass spectrometry and compound-based principal component analysis

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Which human metabolites have we MIST? Retrospective analysis, practical aspects, and perspectives for metabolite identification and quantification in pharmaceutical development.

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

'N-in-one' strategy for metabolite identification using a liquid chromatography/hybrid triple quadrupole linear ion trap instrument using multiple dependent product ion scans triggered with full mass scan.

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Metabolic profiling of glucuronides in human urine by LC-MS/MS and partial least-squares discriminant analysis for classification and prediction of gender

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Application of a linear ion trap/orbitrap mass spectrometer in metabolite characterization studies: examination of the human liver microsomal metabolism of the non-tricyclic anti-depressant nefazodone using data-dependent accurate mass measurements

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Anti-AIDS agents. 78. Design, synthesis, metabolic stability assessment, and antiviral evaluation of novel betulinic acid derivatives as potent anti-human immunodeficiency virus (HIV) agents

1 reference

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21 January 2018

Human CYP3A4 and the metabolism of nefazodone and hydroxynefazodone by human liver microsomes and heterologously expressed enzymes

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Liquid chromatography-mass spectrometry in in vitro drug metabolite screening.

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

3-Acrylamide-4-aryloxyindoles: synthesis, biological evaluation and metabolic stability of potent and selective EP3 receptor antagonists.

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Detection and characterization of metabolites in biological matrices using mass defect filtering of liquid chromatography/high resolution mass spectrometry data

1 reference

https://api.crossref.org/works/10.3109%2F00498251003592691

21 January 2018

Identifiers

10.3109/00498251003592691

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 November 2017

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