(Q43154963)

English

The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa

scientific article published on 31 July 2008

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scholarly article

1 reference

Europe PubMed Central

14 November 2017

The crystal structure of thrombin-activable fibrinolysis inhibitor (TAFI) provides the structural basis for its intrinsic activity and the short half-life of TAFIa (English)

1 reference

Europe PubMed Central

14 November 2017

crystal structure

1 reference

based on heuristic

inferred from title

Josep Vendrell i Roca

5

1 reference

Europe PubMed Central

14 November 2017

8

1 reference

Europe PubMed Central

14 November 2017

Francesc Xavier Avilés Puigvert

9

1 reference

Europe PubMed Central

14 November 2017

Irantzu Pallares

object named as

Irantzu Pallares

2

0 references

Herman A Schreuder

object named as

Herman A Schreuder

7

0 references

author name string

Kanchan Anand

1

1 reference

Europe PubMed Central

14 November 2017

Zuzana Valnickova

3

1 reference

Europe PubMed Central

14 November 2017

Trine Christensen

4

1 reference

Europe PubMed Central

14 November 2017

K Ulrich Wendt

6

1 reference

Europe PubMed Central

14 November 2017

language of work or name

0 references

publication date

31 July 2008

1 reference

Europe PubMed Central

14 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

14 November 2017

283

1 reference

Europe PubMed Central

14 November 2017

43

1 reference

Europe PubMed Central

14 November 2017

29416-29423

1 reference

Europe PubMed Central

14 November 2017

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Metallocarboxypeptidases: emerging drug targets in biomedicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

A role for procarboxypepidase U (TAFI) in thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Generation of a stable activated thrombin activable fibrinolysis inhibitor variant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down-regulating fibrinolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

MEROPS: the peptidase database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Likelihood-enhanced fast rotation functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Thrombin and fibrinolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Two naturally occurring variants of TAFI (Thr-325 and Ile-325) differ substantially with respect to thermal stability and antifibrinolytic activity of the enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Carboxypeptidase R is an inactivator of complement-derived inflammatory peptides and an inhibitor of fibrinolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Thrombin-activatable fibrinolysis inhibitor (TAFI, plasma procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Inactivation of active thrombin-activable fibrinolysis inhibitor takes place by a process that involves conformational instability rather than proteolytic cleavage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Plasma and recombinant thrombin-activable fibrinolysis inhibitor (TAFI) and activated TAFI compared with respect to glycosylation, thrombin/thrombomodulin-dependent activation, thermal stability, and enzymatic properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

The three-dimensional structure of human procarboxypeptidase A2. Deciphering the basis of the inhibition, activation and intrinsic activity of the zymogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Carboxypeptidase U, a plasma carboxypeptidase with high affinity for plasminogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Purification and characterization of TAFI, a thrombin-activable fibrinolysis inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Purification and characterization of a new arginine carboxypeptidase in human serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Three-dimensional structure of porcine procarboxypeptidase B: a structural basis of its inactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

25 May 2018

Post-translational modifications of human thrombin-activatable fibrinolysis inhibitor (TAFI): evidence for a large shift in the isoelectric point and reduced solubility upon activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

15 August 2018

TAFI: a promising drug target?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

15 August 2018

Role of zinc ions in activation and inactivation of thrombin-activatable fibrinolysis inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662027

15 August 2018

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804003200

21 January 2018

Comparative evaluation of stable TAFIa variants: importance of alpha-helix 9 and beta-sheet 11 for TAFIa (in)stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18669641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of thermal instability and proteolytic cleavage in regulation of activated thrombin-activable fibrinolysis inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18669641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible carboxypeptidase activity. A role in clot lysis in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18669641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of plasmin-mediated activation of plasma procarboxypeptidase B. Modulation by glycosaminoglycans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18669641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial plasmin-degradation of fibrin as the basis of a positive feed-back mechanism in fibrinolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18669641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intrinsic enzymatic activity of plasma procarboxypeptidase U (TAFI) can interfere with plasma carboxypeptidase N assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/18669641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M804003200

1 reference

Europe PubMed Central

14 November 2017

1 reference

Europe PubMed Central

14 November 2017

1 reference

Europe PubMed Central

14 November 2017

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