(Q43162171)

English

Effects of A‐317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration

scientific article published on November 17, 2003

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration (English)

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Effects of A‐317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration (English)

1 reference

10.1038/SJ.BJP.0705574

https://api.crossref.org/works/10.1038/SJ.BJP.0705574

3 April 2024

author name string

Steve McGaraughty

1

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Joseph Mikusa

4

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Prisca Honore

5

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Chih-Hung Lee

7

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Carol T. Wismer

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623769

3 April 2024

Chang Z. Zhu

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623769

3 April 2024

Katharine L. Chu

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623769

3 April 2024

Connie R. Faltynek

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623769

3 April 2024

Michael F. Jarvis

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623769

3 April 2024

language of work or name

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publication date

17 November 2003

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

full work available at URL

https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1038/sj.bjp.0705574

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623769

3 April 2024

https://europepmc.org/articles/PMC1574160

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623769

3 April 2024

https://europepmc.org/articles/PMC1574160?pdf=render

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623769

3 April 2024

https://doi.org/10.1038/sj.bjp.0705574

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14623769

3 April 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1038%2Fsj.bjp.0705574

1 reference

10.1038/SJ.BJP.0705574

https://api.crossref.org/works/10.1038/SJ.BJP.0705574

3 April 2024

https://bpspubs.onlinelibrary.wiley.com/doi/pdf/10.1038/sj.bjp.0705574

1 reference

10.1038/SJ.BJP.0705574

https://api.crossref.org/works/10.1038/SJ.BJP.0705574

3 April 2024

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

140

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

8

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

1381-1388

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Purine and pyrimidine (P2) receptors as drug targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Cell damage excites nociceptors through release of cytosolic ATP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Selective activation of nociceptors by P2X receptor agonists in normal and inflamed rat skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP-ATP and enhancement by the P2X(3) allosteric modulator, cibacron blue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Effects of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan-inflamed and neuropathic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

In vivo pathway of thermal hyperalgesia by intrathecal administration of alpha,beta-methylene ATP in mouse spinal cord: involvement of the glutamate-NMDA receptor system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Receptors for purines and pyrimidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Acute nociception mediated by hindpaw P2X receptor activation in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Distinct ATP receptors on pain-sensing and stretch-sensing neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Purinergic receptors: their role in nociception and primary afferent neurotransmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Cloning OF P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Differential distribution of two ATP-gated channels (P2X receptors) determined by immunocytochemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

A unifying purinergic hypothesis for the initiation of pain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Antinociceptive effect of intrathecally administered P2-purinoceptor antagonists in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

A P2X purinoceptor expressed by a subset of sensory neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Efficient analysis of experimental observations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

25 May 2018

Distinct neurochemical mechanisms are activated following administration of different P2X receptor agonists into the hindpaw of a rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Alteration of dorsal root ganglion P2X3 receptor expression and function following spinal nerve ligation in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Functional downregulation of P2X3 receptor subunit in rat sensory neurons reveals a significant role in chronic neuropathic and inflammatory pain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Adenosine 5'-triphosphate inhibits slow depolarization induced by repetitive dorsal root stimulation via P2Y purinoceptors in substantia gelatinosa neurons of the adult rat spinal cord slices with the dorsal root attached

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Peripheral inflammation sensitizes P2X receptor-mediated responses in rat dorsal root ganglion neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Depletion of substance P from rat primary sensory neurons by ATP, an implication of P2X receptor-mediated release of substance P.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Presynaptic P2X receptors facilitate inhibitory GABAergic transmission between cultured rat spinal cord dorsal horn neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Pharmacological characterization of recombinant human and rat P2X receptor subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Immunocytochemical localization of P2X3 purinoceptors in sensory neurons in naive rats and following neuropathic injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1574160

15 August 2018

Modulatory roles of the adenosine triphosphate P2x-purinoceptor in generation of the persistent nociception induced by subcutaneous bee venom injection in the conscious rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP P2X receptors play little role in the maintenance of neuropathic hyperalgesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the development of allodynia by intrathecally administered P2 purinoceptor agonists and antagonists in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete inhibition of purinoceptor agonist-induced nociception by spinorphin, but not by morphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical allodynia caused by intraplantar injection of P2X receptor agonist in rats: involvement of heteromeric P2X2/3 receptor signaling in capsaicin-insensitive primary afferent neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic transmission between dorsal root ganglion and dorsal horn neurons in culture: antagonism of monosynaptic excitatory postsynaptic potentials and glutamate excitation by kynurenate

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcutaneous formalin-induced activity of dorsal horn neurones in the rat: differential response to an intrathecal opiate administered pre or post formalin

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP modulation of synaptic transmission in the spinal substantia gelatinosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral adenosine 5′-triphosphate enhances nociception in the formalin test via activation of a purinergic p2X receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of cultured dorsal root ganglion neuron P2X receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14623769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0705574

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

ResearchGate publication ID

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