(Q43165733)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Angiostatic effects of K252a, a Trk inhibitor, in murine brain capillary endothelial cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1

1 reference

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18 January 2020

author name string

Hadar Arien-Zakay

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Martin Kohan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Peter I Lelkes

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Philip Lazarovici

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

11 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biochemistry

18 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

1-2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

201-213

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20148355%20AND%20SRC:MED&resulttype=core&format=json

Nerve growth factor as a signaling molecule for nerve cells and also for the neuroendocrine-immune systems

18 January 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-010-0386-9

Nerve growth factor and diabetic neuropathy

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-010-0386-9

Mitogenesis in glioblastoma multiforme cell lines: a role for NGF and its TrkA receptors

21 January 2018

1 reference

12 December 2020

Nerve growth factor-induced protection of brain capillary endothelial cells exposed to oxygen-glucose deprivation involves attenuation of Erk phosphorylation.

1 reference

12 December 2020

The Protective Effects of Preconditioning on Cerebral Endothelial Cells in Vitro

1 reference

12 December 2020

Brain capillary endothelial cells proliferate in response to NGF, express NGF receptors and secrete NGF after inflammation

1 reference

12 December 2020

Role of neurotrophin-trk interactions in oncology: the anti-tumor efficacy of potent and selective trk tyrosine kinase inhibitors in pre-clinical tumor models

1 reference

12 December 2020

K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors

1 reference

12 December 2020

Paracrine and autocrine functions of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in brain-derived endothelial cells

1 reference

12 December 2020

Expression and activation of the nerve growth factor receptor TrkA in serous ovarian carcinoma

1 reference

12 December 2020

Molecular basis for sunitinib efficacy and future clinical development

1 reference

12 December 2020

Tyrosine kinase inhibitor CEP-701 blocks the NTRK1/NGF receptor and limits the invasive capability of prostate cancer cells in vitro.

1 reference

12 December 2020

Nilotinib: a phenylamino-pyrimidine derivative with activity against BCR-ABL, KIT and PDGFR kinases

1 reference

12 December 2020

Simvastatin suppresses coronary artery endothelial tube formation by disrupting Ras/Raf/ERK signaling

1 reference

12 December 2020

The topical application of nerve growth factor as a pharmacological tool for human corneal and skin ulcers.

1 reference

12 December 2020

Cardiac microvascular endothelial cells express and release nerve growth factor but not fibroblast growth factor-2.

1 reference

12 December 2020

Angiogenesis: an organizing principle for drug discovery?

1 reference

12 December 2020

K252a inhibits proliferation of ovarian cancer cells by upregulating p21WAF1.

1 reference

12 December 2020

Probing the binding mechanism and affinity of tanezumab, a recombinant humanized anti-NGF monoclonal antibody, using a repertoire of biosensors

1 reference

12 December 2020

K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK.

1 reference

12 December 2020

Enhanced osteopontin expression in a murine model of allergen-induced airway remodelling

1 reference

12 December 2020

Glial extracellular matrix modulates gamma-glutamyl transpeptidase activity in cultured bovine brain capillary and bovine aortic endothelial cells

1 reference

12 December 2020

Neurotrophin signal transduction in the nervous system

1 reference

12 December 2020

Effect of K252a, a protein kinase inhibitor, on the proliferation of vascular smooth muscle cells.

1 reference

12 December 2020

Molecular pathways of angiogenesis inhibition

1 reference

12 December 2020

Signaling pathways for PC12 cell differentiation: making the right connections

1 reference

12 December 2020

Nerve growth factor as an angiogenic factor.

1 reference

12 December 2020

Induction of giant endothelial cells in culture by K-252a, a protein kinase inhibitor

1 reference

12 December 2020

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

1 reference

12 December 2020

Therapeutic options to target angiogenesis in human malignancies

1 reference

12 December 2020

Ascorbic acid stimulates barrier function of cultured endothelial cell monolayer

1 reference

12 December 2020

Identification of novel drug targets for angiostatic cancer therapy; it takes two to tango

1 reference

12 December 2020

Exploitation of protein kinase C: a useful target for cancer therapy

1 reference

12 December 2020

Involvement of neurotrophins and growth factors in brain metastasis formation

1 reference

12 December 2020

A quantitative bioassay for nerve growth factor, using PC12 clones expressing different levels of trkA receptors

1 reference

12 December 2020

α1A-Adrenoceptor subtype effectively increases Ca2+-sensitivity for contraction in rabbit thoracic aorta

1 reference

12 December 2020

Quantitative assessment of neuronal differentiation in three-dimensional collagen gels using enhanced green fluorescence protein expressing PC12 pheochromocytoma cells.

1 reference

12 December 2020

The dark side of the NGF family: neurotrophins in neoplasias

1 reference

12 December 2020

The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.

1 reference

12 December 2020

Novel function of ascorbic acid as an angiostatic factor

1 reference

12 December 2020

Targeting angiogenesis: progress with anti-VEGF treatment with large molecules

1 reference

12 December 2020

Discovery and development of sorafenib: a multikinase inhibitor for treating cancer.

1 reference

12 December 2020

Nerve growth factor overexpression and autocrine loop in breast cancer cells

1 reference

12 December 2020

K252a is highly effective in suppressing the growth of human endometrial cancer cells, but has little effect on normal human endometrial epithelial cells

1 reference

12 December 2020

Neurovascular signalling defects in neurodegeneration

1 reference

12 December 2020

FLT3 kinase inhibitors in the management of acute myeloid leukemia.

1 reference

12 December 2020

Nerve growth factor in neurological and non-neurological diseases: basic findings and emerging pharmacological prospectives.

1 reference

12 December 2020

The impact of glia-derived extracellular matrices on the barrier function of cerebral endothelial cells: an in vitro study

1 reference

12 December 2020

Nerve growth factor-endothelial cell interaction leads to angiogenesis in vitro and in vivo

1 reference

12 December 2020

Regulation of extracellular matrix remodeling and MMP-2 activation in cultured rat adrenal medullary endothelial cells

1 reference

12 December 2020

Nerve growth factor control of neuronal expression of angiogenetic and vasoactive factors.

1 reference

12 December 2020

K252a inhibits the oncogenic properties of Met, the HGF receptor

1 reference

12 December 2020

Neuroprotection by cord blood neural progenitors involves antioxidants, neurotrophic and angiogenic factors

1 reference

12 December 2020

Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood-brain barrier model for drug uptake and transport studies

1 reference

12 December 2020

Cross talk between the cardiovascular and nervous systems: neurotrophic effects of vascular endothelial growth factor (VEGF) and angiogenic effects of nerve growth factor (NGF)-implications in drug development

1 reference

12 December 2020

Suppression of the Raf/MEK/ERK signaling cascade and inhibition of angiogenesis by the carboxyl terminus of angiopoietin-like protein 4.

1 reference

12 December 2020

Intracellular mechanisms involved in basement membrane induced blood vessel differentiation in vitro

1 reference

12 December 2020