(Q37078102)

18 August 2017

1 reference

title

Neurovascular signalling defects in neurodegeneration (English)

1 reference

18 August 2017

1 reference

2

Diether Lambrechts

1 reference

18 August 2017

3

Peter Carmeliet

1 reference

18 August 2017

1

Serena Zacchigna

1 reference

18 August 2017

language of work or name

English

0 references

publication date

1 March 2008

1 reference

Nature Reviews Neuroscience

18 August 2017

published in

1 reference

18 August 2017

volume

9

1 reference

18 August 2017

issue

3

1 reference

18 August 2017

page(s)

169-181

1 reference

https://scigraph.springernature.com/pub.10.1038/nrn2336

18 August 2017

exact match

0 references

cites work

Condensation of the central nervous system in embryonic Drosophila is inhibited by blocking hemocyte migration or neural activity

1 reference

Caenorhabditis elegans receptors related to mammalian vascular endothelial growth factor receptors are expressed in neural cells

31 March 2020

1 reference

Alzheimer's disease is a vasocognopathy: a new term to describe its nature

31 March 2020

1 reference

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

31 March 2020

1 reference

Angiogenesis in multiple sclerosis: is it good, bad or an epiphenomenon?

31 March 2020

1 reference

Endothelial proliferation and increased blood-brain barrier permeability in the basal ganglia in a rat model of 3,4-dihydroxyphenyl-L-alanine-induced dyskinesia.

31 March 2020

1 reference

Blood-brain barrier dysfunction in parkinsonian midbrain in vivo

31 March 2020

1 reference

PET imaging of cerebral perfusion and oxygen consumption in acute ischaemic stroke: relation to outcome

31 March 2020

1 reference

Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy

31 March 2020

1 reference

Impaired endothelial function in coronary heart disease patients with depressive symptomatology

31 March 2020

1 reference

Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration

31 March 2020

1 reference

Therapeutic angiogenesis inhibits or rescues chemotherapy-induced peripheral neuropathy: taxol- and thalidomide-induced injury of vasa nervorum is ameliorated by VEGF.

31 March 2020

1 reference

Neurotrophins: roles in neuronal development and function

31 March 2020

1 reference

Brain-derived neurotrophic factor: a newly described mediator of angiogenesis

31 March 2020

1 reference

Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

31 March 2020

1 reference

Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.

31 March 2020

1 reference

Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra

31 March 2020

1 reference

Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

31 March 2020

1 reference

Blood vessels and nerves: common signals, pathways and diseases

31 March 2020

1 reference

Identification of novel mutations in the SEMA4A gene associated with retinal degenerative diseases

31 March 2020

1 reference

Mechanisms of angiogenesis and arteriogenesis

31 March 2020

1 reference

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

31 March 2020

1 reference

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

31 March 2020

1 reference

Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed to hypoxia

31 March 2020

1 reference

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

31 March 2020

1 reference

VEGF-overexpressing transgenic mice show enhanced post-ischemic neurogenesis and neuromigration

31 March 2020

1 reference

Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish

31 March 2020

1 reference

Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration

31 March 2020

1 reference

VEGF gene and phenotype relation with Alzheimer's disease and mild cognitive impairment.

31 March 2020

1 reference

Co-accumulation of vascular endothelial growth factor with beta-amyloid in the brain of patients with Alzheimer's disease

31 March 2020

1 reference

Disturbed cross talk between insulin-like growth factor I and AMP-activated protein kinase as a possible cause of vascular dysfunction in the amyloid precursor protein/presenilin 2 mouse model of Alzheimer's disease

31 March 2020

1 reference

Lack of hypoxia-inducible factor-1 alpha impairs midbrain neural precursor cells involving vascular endothelial growth factor signaling

31 March 2020

1 reference

Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury.

31 March 2020

1 reference

Mouse brains deficient in neuronal PDGF receptor-beta develop normally but are vulnerable to injury.

31 March 2020

1 reference

ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis.

31 March 2020

1 reference

Another angiogenic gene linked to amyotrophic lateral sclerosis

31 March 2020

1 reference

A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis

31 March 2020

1 reference

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

31 March 2020

1 reference

Progranulin is a mediator of the wound response

31 March 2020

1 reference

PC cell-derived growth factor (PCDGF/GP88, progranulin) stimulates migration, invasiveness and VEGF expression in breast cancer cells

31 March 2020

1 reference

Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology

31 March 2020

1 reference

Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain

31 March 2020

1 reference

Molecular and functional dissection of TGF-beta1-induced cerebrovascular abnormalities in transgenic mice

31 March 2020

1 reference

Reduced brain tissue perfusion in TGF-beta 1 transgenic mice showing Alzheimer's disease-like cerebrovascular abnormalities

31 March 2020

1 reference

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

31 March 2020

1 reference

Loss of basic fibroblast growth factor in substantia nigra neurons in Parkinson's disease.

31 March 2020

1 reference

Whisker stimulation enhances angiogenesis in the barrel cortex following focal ischemia in mice.

31 March 2020

1 reference

Autocrine VEGF signaling is required for vascular homeostasis

31 March 2020

1 reference

Direct evidence for endothelial vascular endothelial growth factor receptor-1 function in nitric oxide-mediated angiogenesis

31 March 2020

1 reference

Neurovascular mechanisms of Alzheimer's neurodegeneration

31 March 2020

1 reference

Transforming growth factor-beta1 upregulates the tight junction and P-glycoprotein of brain microvascular endothelial cells

31 March 2020

1 reference

Hepatocyte growth factor attenuates cerebral ischemia-induced increase in permeability of the blood-brain barrier and decreases in expression of tight junctional proteins in cerebral vessels.

31 March 2020

1 reference

Basic fibroblast growth factor modulates density of blood vessels and preserves tight junctions in organotypic cortical cultures of mice: a new in vitro model of the blood-brain barrier.

31 March 2020

1 reference

Functions of fibroblast growth factor (FGF)-2 and FGF-5 in astroglial differentiation and blood-brain barrier permeability: evidence from mouse mutants

31 March 2020

1 reference

HIF activation and VEGF overexpression are coupled with ZO-1 up-phosphorylation in the brain of dystrophic mdx mouse

31 March 2020

1 reference

Vascular endothelial growth factor (VEGF) in seizures: a double-edged sword

31 March 2020

1 reference

Blood-brain barrier disruption induces in vivo degeneration of nigral dopaminergic neurons

31 March 2020

1 reference

Excessive erythrocytosis in adult mice overexpressing erythropoietin leads to hepatic, renal, neuronal, and muscular degeneration.

31 March 2020

1 reference

VEGF at the neurovascular interface: therapeutic implications for motor neuron disease

31 March 2020

1 reference

Fibroblast growth factor receptor-1 is required for long-term potentiation, memory consolidation, and neurogenesis

31 March 2020

1 reference

The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease

31 March 2020

1 reference

Depression of synaptic transmission by vascular endothelial growth factor in adult rat hippocampus and evidence for increased efficacy after chronic seizures.

31 March 2020

1 reference

Enhancement of ischemia-induced tyrosine phosphorylation of Kv1.2 by vascular endothelial growth factor via activation of phosphatidylinositol 3-kinase.

31 March 2020

1 reference

GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action

31 March 2020

1 reference

A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor

31 March 2020

1 reference

Onset and progression in inherited ALS determined by motor neurons and microglia

31 March 2020

1 reference

Mutant Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis destabilizes vascular endothelial growth factor mRNA and downregulates its expression

31 March 2020

1 reference

Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila.

31 March 2020

1 reference

Physiological function and putative therapeutic impact of the FGF-2 system in peripheral nerve regeneration--lessons from in vivo studies in mice and rats.

31 March 2020

1 reference

A neurovascular niche for neurogenesis after stroke.

31 March 2020

1 reference

VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants

31 March 2020

1 reference

VEGF links hippocampal activity with neurogenesis, learning and memory

31 March 2020

1 reference

VEGF is necessary for exercise-induced adult hippocampal neurogenesis

31 March 2020

1 reference

VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia

31 March 2020

1 reference

Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain.

31 March 2020

1 reference

Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk-1 protein expression.

31 March 2020

1 reference

Neural stem cells LewisX+ CXCR4+ modify disease progression in an amyotrophic lateral sclerosis model.

31 March 2020

1 reference

Chronically increased transforming growth factor-beta1 strongly inhibits hippocampal neurogenesis in aged mice

31 March 2020

1 reference

Ephrin-A2 reverse signaling negatively regulates neural progenitor proliferation and neurogenesis

31 March 2020

1 reference

EphrinB3 regulates cell proliferation and survival in adult neurogenesis

31 March 2020

1 reference

Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease

31 March 2020

1 reference

Vascular endothelial growth factor inhibits outward delayed-rectifier potassium currents in acutely isolated hippocampal neurons

31 March 2020

1 reference

Transforming growth factor-beta 1 regulates Kir2.3 inward rectifier K+ channels via phospholipase C and protein kinase C-delta in reactive astrocytes from adult rat brain

31 March 2020

1 reference

TGF-beta1-induced long-term changes in neuronal excitability in aplysia sensory neurons depend on MAPK

31 March 2020

1 reference

Hepatocyte growth factor as an enhancer of nmda currents and synaptic plasticity in the hippocampus

31 March 2020

1 reference

Interaction between interferon gamma and insulin-like growth factor-1 in hippocampus impacts on the ability of rats to sustain long-term potentiation.

31 March 2020

1 reference

Epidermal growth factor and basic fibroblast growth factor promote the generation of long-term potentiation in the dentate gyrus of anaesthetized rats

31 March 2020

1 reference

Fibroblast growth factor-2 increases functional excitatory synapses on hippocampal neurons

31 March 2020

1 reference

Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development

31 March 2020

1 reference

The yin and yang of neurotrophin action

31 March 2020

1 reference

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

31 March 2020

1 reference

Terminal Schwann cells guide the reinnervation of muscle after nerve injury

31 March 2020

1 reference

The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease

31 March 2020

1 reference

Target-derived trophic effect on skeletal muscle innervation in senescent mice

31 March 2020

1 reference

Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model

31 March 2020

1 reference

IGF-I specifically enhances axon outgrowth of corticospinal motor neurons.

31 March 2020

1 reference

Fibroblast growth factor-2 promotes axon branching of cortical neurons by influencing morphology and behavior of the primary growth cone.

31 March 2020

1 reference

Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors

31 March 2020

1 reference

Poor and protracted myelination as a contributory factor to neurodegenerative disorders

31 March 2020

1 reference

Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy

31 March 2020

1 reference

Combination of growth factors enhances remyelination in a cuprizone-induced demyelination mouse model.

31 March 2020

1 reference

Schwann cells express erythropoietin receptor and represent a major target for Epo in peripheral nerve injury

31 March 2020

1 reference

Insulin-like growth factor type 1 receptor signaling in the cells of oligodendrocyte lineage is required for normal in vivo oligodendrocyte development and myelination

31 March 2020

1 reference

PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination

31 March 2020

1 reference

Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination

31 March 2020

1 reference

VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain

31 March 2020

1 reference

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

31 March 2020

1 reference

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

31 March 2020

1 reference

Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS.

31 March 2020

1 reference

IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1.

31 March 2020

1 reference

Vascular endothelial growth factor stimulates skeletal muscle regeneration in vivo

31 March 2020

1 reference

Fibroblast growth factor-2-producing fibroblasts protect the nigrostriatal dopaminergic system from 6-hydroxydopamine

31 March 2020

1 reference

Prevention of onset of Parkinson's disease by in vivo gene transfer of human hepatocyte growth factor in rodent model: a model of gene therapy for Parkinson's disease

31 March 2020

1 reference

The differences between high and low-dose administration of VEGF to dopaminergic neurons of in vitro and in vivo Parkinson's disease model

31 March 2020

1 reference

Enhanced vascularization and survival of neural transplants with ex vivo angiogenic gene transfer.

31 March 2020

1 reference

Enhanced survival, reinnervation, and functional recovery of intrastriatal dopamine grafts co-transplanted with Schwann cells overexpressing high molecular weight FGF-2 isoforms

31 March 2020

1 reference

Stem cells for the treatment of neurological disorders

31 March 2020

1 reference

FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease

31 March 2020

1 reference

Alterations in seizure susceptibility and in seizure-induced plasticity after pharmacologic and genetic manipulation of the fibroblast growth factor-2 system.

31 March 2020

1 reference

Fibroblast growth factor-II gene therapy reverts the clinical course and the pathological signs of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice.

31 March 2020

1 reference

Delayed administration of erythropoietin and its non-erythropoietic derivatives ameliorates chronic murine autoimmune encephalomyelitis.

31 March 2020

1 reference

Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis

31 March 2020

1 reference

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

31 March 2020

1 reference

Growth factors and stroke

31 March 2020

1 reference

Nerve growth factor gene delivery: animal models to clinical trials

31 March 2020

1 reference

Vessels and nerves: marching to the same tune

31 March 2020

1 reference

Common mechanisms of nerve and blood vessel wiring

31 March 2020

1 reference

Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve

31 March 2020

1 reference

Impaired angiogenesis in a transgenic mouse model of cerebral amyloidosis

31 March 2020

1 reference

Amyloid angiopathy-related vascular cognitive impairment.

31 March 2020

1 reference

Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins

31 March 2020

1 reference

Two-photon imaging of astrocytic Ca2+ signaling and the microvasculature in experimental mice models of Alzheimer's disease

31 March 2020

1 reference

Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein

31 March 2020

1 reference

Perfusion abnormalities in prodromal AD.

31 March 2020

1 reference

Neurovascular regulation in the normal brain and in Alzheimer's disease

31 March 2020

1 reference

Finding function in novel targets: C. elegans as a model organism.

31 March 2020

1 reference

VEGF: multitasking in ALS

31 March 2020

1 reference

Endothelial signaling during development

31 March 2020

1 reference

Disruption of a single allele of the nerve growth factor gene results in atrophy of basal forebrain cholinergic neurons and memory deficits

31 March 2020

1 reference

PDGFR alpha-positive B cells are neural stem cells in the adult SVZ that form glioma-like growths in response to increased PDGF signaling

31 March 2020

1 reference

Neurotrophic factors in neurodegenerative disorders: model of Parkinson's disease.

31 March 2020

1 reference

Angels and demons: neurotrophic factors and epilepsy.

31 March 2020

1 reference

Hippocampal vulnerability following traumatic brain injury: a potential role for neurotrophin-4/5 in pyramidal cell neuroprotection.

31 March 2020

1 reference

Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors.

31 March 2020

1 reference

Reversal of experimental diabetic neuropathy by VEGF gene transfer

31 March 2020

1 reference

Angiogenin activates Erk1/2 in human umbilical vein endothelial cells

31 March 2020

1 reference

Angiogenin activates human umbilical artery smooth muscle cells

31 March 2020

1 reference

Human angiogenin is a neuroprotective factor and amyotrophic lateral sclerosis associated angiogenin variants affect neurite extension/pathfinding and survival of motor neurons.

31 March 2020

1 reference

Initiation to end point: the multiple roles of fibroblast growth factors in neural development

31 March 2020

1 reference

TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling

31 March 2020

1 reference

Endocrine, liver-derived IGF-I is of importance for spatial learning and memory in old mice.

31 March 2020

1 reference

Mechanical stretch simulates proliferation of venous smooth muscle cells through activation of the insulin-like growth factor-1 receptor.

31 March 2020

1 reference

Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction.

31 March 2020

1 reference

Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS

31 March 2020

1 reference

Nonviral gene transfer of human hepatocyte growth factor improves streptozotocin-induced diabetic neuropathy in rats

31 March 2020

1 reference

Potential role of a novel vascular modulator, hepatocyte growth factor (HGF), in cardiovascular disease: characterization and regulation of local HGF system

31 March 2020

1 reference

Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons

31 March 2020

1 reference

Tumor endothelial cells express epidermal growth factor receptor (EGFR) but not ErbB3 and are responsive to EGF and to EGFR kinase inhibitors

31 March 2020

1 reference

Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation

31 March 2020

1 reference

Neuroprotective effects of erythropoietin in the rat hippocampus after pilocarpine-induced status epilepticus

31 March 2020

1 reference

Derivatives of erythropoietin that are tissue protective but not erythropoietic

31 March 2020

1 reference

Role of erythropoietin in the brain

31 March 2020

1 reference

Basic Fibroblast Growth Factor Selectively Increases AMPA‐Receptor Subunit GluR1 Protein Level and Differentially Modulates Ca2+ Responses to AMPA and NMDA in Hippocampal Neurons

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRN2336

1 reference

18 August 2017

1 reference