(Q48110101)

8 February 2018

title

Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain. (English)

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8 February 2018

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3

Eliezer Masliah

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8 February 2018

4

Tony Wyss-Coray

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8 February 2018

author name string

Thomas C Brionne

series ordinal

1

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8 February 2018

Ina Tesseur

series ordinal

2

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8 February 2018

language of work or name

English

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publication date

1 December 2003

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8 February 2018

published in

Neuron

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8 February 2018

volume

40

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8 February 2018

page(s)

1133-1145

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8 February 2018

issue

6

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8 February 2018

TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death.

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Transforming growth factor beta has neurotrophic actions on sensory neurons in vitro and is synergistic with nerve growth factor

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7 January 2021

Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin.

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7 January 2021

TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu

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7 January 2021

Early-onset multifocal inflammation in the transforming growth factor beta 1-null mouse is lymphocyte mediated

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7 January 2021

Bone morphogenetic proteins and their receptors: potential functions in the brain

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7 January 2021

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

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7 January 2021

A receptor for phosphatidylserine-specific clearance of apoptotic cells

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7 January 2021

Transforming growth factor-beta(s) are essential for the development of midbrain dopaminergic neurons in vitro and in vivo.

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7 January 2021

TGF-beta 1 is an organizer of responses to neurodegeneration

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7 January 2021

Transforming growth factor-betas in neurodegenerative disease

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7 January 2021

Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages

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7 January 2021

Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype

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7 January 2021

Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein

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7 January 2021

Genetic control of the circulating concentration of transforming growth factor type beta1

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7 January 2021

High and low annealing temperatures increase both specificity and yield in touchdown and stepdown PCR.

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7 January 2021

Neurotrophins: roles in neuronal development and function

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7 January 2021

Laminin chain expression suggests that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury

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7 January 2021

Molecular mechanisms of developmental neuronal death

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7 January 2021

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.

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7 January 2021

Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex

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7 January 2021

Short communication: transforming growth factor-beta mediates the neurotrophic effect of fibroblast growth factor-2 on midbrain dopaminergic neurons.

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7 January 2021

Reduction of endogenous transforming growth factors beta prevents ontogenetic neuron death

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7 January 2021

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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7 January 2021

Murine models define the role of TGF-beta as a master regulator of immune cell function

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7 January 2021

TGF-beta: a critical modulator of immune cell function

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7 January 2021

Regulation of immune responses by TGF-beta

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7 January 2021

Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression

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7 January 2021

Endocrine expression of the active form of TGF-beta1 in the TGF-beta1 null mice fails to ameliorate lethal phenotype

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7 January 2021

Laminin and the mechanism of neuronal outgrowth

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7 January 2021

Spectrum of human immunodeficiency virus-associated neocortical damage

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7 January 2021

Neurodegeneration in the central nervous system of apoE-deficient mice

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7 January 2021

TGFbeta signaling in growth control, cancer, and heritable disorders

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7 January 2021

Transforming growth factor beta: a matter of life and death

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7 January 2021

Bone morphogenetic proteins in the nervous system

1 reference

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7 January 2021

TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons.

1 reference

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7 January 2021

RAG-1-deficient mice have no mature B and T lymphocytes

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7 January 2021

Latent transforming growth factor-beta: structural features and mechanisms of activation

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7 January 2021

Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches

1 reference

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7 January 2021

Glial cell line-derived neurotrophic factor rescues target-deprived sympathetic spinal cord neurons but requires transforming growth factor-beta as cofactor in vivo.

1 reference

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7 January 2021

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

1 reference

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7 January 2021

Transforming growth factor-beta1 enhances expression of brain-derived neurotrophic factor and its receptor, TrkB, in neurons cultured from rat cerebral cortex

1 reference

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7 January 2021

Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation.

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7 January 2021

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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7 January 2021

Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

Neuronal cell death and tPA.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

Co-activation of TGF-ss and cytokine signaling pathways are required for neurotrophic functions

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

TGF-betas and their roles in the regulation of neuron survival

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

Extracellular matrix. 2: Role of extracellular matrix molecules and their receptors in the nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

Functions of mammalian Smad genes as revealed by targeted gene disruption in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

Role of transforming growth factor-beta in long-term synaptic facilitation in Aplysia

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

TGF-beta signaling activates steroid hormone receptor expression during neuronal remodeling in the Drosophila brain

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2803%2900766-9

7 January 2021

10.1016/S0896-6273(03)00766-9

Identifiers

DOI

1 reference

8 February 2018

PubMed ID

14687548

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8 February 2018