(Q49168922)

18 February 2018

review article

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title

Finding function in novel targets: C. elegans as a model organism (English)

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18 February 2018

main subject

Caenorhabditis elegans

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Michael Otmar Hengartner

object named as

Michael O Hengartner

series ordinal

2

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author name string

Titus Kaletta

series ordinal

1

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18 February 2018

publication date

1 May 2006

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18 February 2018

Nature Reviews Drug Discovery

published in

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18 February 2018

volume

5

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18 February 2018

issue

5

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18 February 2018

page(s)

387-398

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18 February 2018

Genome sequence of the nematode C. elegans: a platform for investigating biology

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Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions

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Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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Presenilin is required for proper morphology and function of neurons in C. elegans

31 March 2020

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Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

31 March 2020

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

31 March 2020

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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

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Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

31 March 2020

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Characterization of gana-1, a Caenorhabditis elegans gene encoding a single ortholog of vertebrate alpha-galactosidase and alpha-N-acetylgalactosaminidase

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Characterization of GAR-2, a novel G protein-linked acetylcholine receptor from Caenorhabditis elegans

31 March 2020

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Mutant sensory cilia in the nematode Caenorhabditis elegans

31 March 2020

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31 March 2020

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Fluoxetine-resistance genes in Caenorhabditis elegans function in the intestine and may act in drug transport

31 March 2020

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Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family

31 March 2020

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Effect of vitamin E on lifespan and reproduction in Caenorhabditis elegans

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation

31 March 2020

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BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

31 March 2020

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Transgenic invertebrate models of age-associated neurodegenerative diseases

31 March 2020

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Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans

31 March 2020

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Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein

31 March 2020

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Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans

31 March 2020

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Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

31 March 2020

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Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

31 March 2020

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RNA interference: from model organisms towards therapy for neural and neuromuscular disorders

31 March 2020

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31 March 2020

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Prednisone reduces muscle degeneration in dystrophin-deficient Caenorhabditis elegans

31 March 2020

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SNF-6 is an acetylcholine transporter interacting with the dystrophin complex in Caenorhabditis elegans

31 March 2020

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Glycolipids as receptors for Bacillus thuringiensis crystal toxin

31 March 2020

1 reference

Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRD2031

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18 February 2018

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18 February 2018