(Q43167314)

15 November 2017

title

Non-steroidal glucocorticoid receptor antagonists: the race to replace RU-486 for anti-glucocorticoid therapy (English)

1 reference

15 November 2017

1 reference

Michael L Mohler

1

1 reference

15 November 2017

Yali He

2

1 reference

15 November 2017

Zhongzhi Wu

3

1 reference

15 November 2017

Seoung-Soo Hong

4

1 reference

15 November 2017

Duane D Miller

5

1 reference

15 November 2017

language of work or name

English

0 references

publication date

1 January 2007

1 reference

Expert Opinion on Therapeutic Patents

15 November 2017

published in

1 reference

15 November 2017

volume

17

1 reference

15 November 2017

issue

1

1 reference

15 November 2017

page(s)

59-81

1 reference

Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity

15 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Classic and recent etiologies of Cushing's syndrome: diagnosis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Identification by microarray analysis of aspartate aminotransferase and glutamine synthetase as glucocorticoid target genes in a mouse Schwann cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

The use of mifepristone in the treatment of neuropsychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Cortisol levels and depression in men and women using heroin and cocaine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

RU 486: how abortion politics have impacted on a potentially useful drug of broad medical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Treatment of depression with antiglucocorticoid drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Distinct sequence elements involved in the glucocorticoid regulation of the mouse mammary tumor virus promoter identified by linker scanning mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Discovery of potent, nonsteroidal, and highly selective glucocorticoid receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

A nonsteroidal glucocorticoid receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Discovery of novel nonsteroidal glucocorticoid receptor modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Antidiabetic activity of passive nonsteroidal glucocorticoid receptor modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Trifluoromethyl group as a pharmacophore: effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Synthesis and biological evaluation of novel, selective, nonsteroidal glucocorticoid receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Is AL-438 likely to have fewer side effects than the glucocorticoids?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Discovery and SAR study of novel dihydroquinoline containing glucocorticoid receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Gene regulation profiles by progesterone and dexamethasone in human endometrial cancer Ishikawa H cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Glucocorticoid Receptor Antagonism by Cyproterone Acetate and RU486

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Design of thyroid hormone receptor antagonists from first principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Molecular basis of agonism and antagonism in the oestrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Liver-selective glucocorticoid antagonists: a novel treatment for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

Effects of the glucocorticoid antagonist RU 486 on pituitary-adrenal function in patients with anorexia nervosa and healthy volunteers: enhancement of plasma ACTH and cortisol secretion in underweight patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.17.1.59

21 January 2018

Identifiers

DOI

10.1517/13543776.17.1.59

1 reference

15 November 2017

1 reference