(Q43167728)

English

A novel approach for organelle-specific DNA damage targeting reveals different susceptibility of mitochondrial DNA to the anticancer drugs camptothecin and topotecan

scientific article published on 16 January 2009

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scholarly article

1 reference

Europe PubMed Central

15 November 2017

A novel approach for organelle-specific DNA damage targeting reveals different susceptibility of mitochondrial DNA to the anticancer drugs camptothecin and topotecan (English)

1 reference

Europe PubMed Central

15 November 2017

0 references

mitochondrial DNA

0 references

author name string

M C Díaz de la Loza

1

1 reference

Europe PubMed Central

15 November 2017

R E Wellinger

2

1 reference

Europe PubMed Central

15 November 2017

language of work or name

0 references

publication date

16 January 2009

1 reference

Europe PubMed Central

15 November 2017

Nucleic Acids Research

1 reference

Europe PubMed Central

15 November 2017

37

1 reference

Europe PubMed Central

15 November 2017

4

1 reference

Europe PubMed Central

15 November 2017

e26

1 reference

Europe PubMed Central

15 November 2017

Mitotic phosphorylation stimulates DNA relaxation activity of human topoisomerase I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Mitochondrial topoisomerases and alternative splicing of the human TOP1mt gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Nuclear and mitochondrial DNA repair: similar pathways?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Novel camptothecin derivatives.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

The impact of tumor physiology on camptothecin-based drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Residues 190-210 of human topoisomerase I are required for enzyme activity in vivo but not in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Repair of and checkpoint response to topoisomerase I-mediated DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Global analysis of protein localization in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Mitochondrial DNA repair and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

The curious history of yeast mitochondrial DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Enzymology of mitochondrial base excision repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Human mitochondrial topoisomerase I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

DNA relaxation and cleavage assays to study topoisomerase I inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Mammalian DNA single-strand break repair: an X-ra(y)ted affair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

A novel nuclear localization signal in human DNA topoisomerase I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

A model for the mechanism of human topoisomerase I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Camptothecin and taxol: from discovery to clinic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

A novel mutation in DNA topoisomerase I of yeast causes DNA damage and RAD9-dependent cell cycle arrest.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

The mechanisms of DNA topoisomerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Cytoplasmic “Petite” Induction in Recombination-Deficient Mutants of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Rapid purification and structural study of DNA topoisomerase I from human Burkitt lymphoma Raji cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Multifunctional yeast high-copy-number shuttle vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Genetic homology between Saccharomyces cerevisiae and its sibling species S. paradoxus and S. bayanus: electrophoretic karyotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

25 May 2018

Enhancement of DNA topoisomerase I inhibitor-induced apoptosis by ursodeoxycholic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

15 August 2018

On the electronic structure of ethidium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

15 August 2018

Subcellular localization of the camptothecin analogues, topotecan and gimatecan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

15 August 2018

On the relationship of the ATP-independent, mitochondrial associated DNA topoisomerase of Saccharomyces cerevisiae to the nuclear topoisomerase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

15 August 2018

Camptothecin inhibits both the cleavage and religation reactions of eukaryotic DNA topoisomerase I

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKN1087

21 January 2018

Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651790

1 December 2018

Duplication of leader sequence for protein targeting to mitochondria leads to increased import efficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/19151088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Equilibrium kinetics of the new experimental anti-tumour compound SK&F 104864-A in aqueous solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/19151088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and antitumor activity of 20(S)-camptothecin derivatives: carbamate-linked, water-soluble derivatives of 7-ethyl-10-hydroxycamptothecin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19151088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a nucleotide-dependent topoisomerase activity from yeast mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19151088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/19151088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA topoisomerase I of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19151088

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKN1087

1 reference

Europe PubMed Central

15 November 2017

1 reference

Europe PubMed Central

15 November 2017

1 reference

Europe PubMed Central

15 November 2017

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0 references

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