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Residues 190-210 of human topoisomerase I are required for enzyme activity in vivo but not in vitro
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
title
Residues 190-210 of human topoisomerase I are required for enzyme activity in vivo but not in vitro
(English)
1 reference
stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
main subject
DNA topoisomerase I
1 reference
stated in
GOA release 2020-03-11
supercoiled DNA binding
1 reference
stated in
GOA release 2020-03-11
author
Fritz Boege
series ordinal
3
object named as
Fritz Boege
0 references
author name string
Morten O. Christensen
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
Hans U. Barthelmes
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
Christian Mielke
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
language of work or name
English
0 references
publication date
15 December 2003
1 reference
stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
published in
Nucleic Acids Research
1 reference
stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
volume
31
1 reference
stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
issue
24
1 reference
stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
page(s)
7255–7263
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stated in
PubMed
PubMed ID
14654701
retrieved
7 March 2017
cites work
Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog
1 reference
stated in
PubMed Central
reference URL
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16 March 2017
The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
Subnuclear distribution of topoisomerase I is linked to ongoing transcription and p53 status
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
DNA topoisomerases: structure, function, and mechanism
1 reference
stated in
PubMed Central
reference URL
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retrieved
16 March 2017
A novel nuclear localization signal in human DNA topoisomerase I
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
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16 March 2017
Role for nucleolin/Nsr1 in the cellular localization of topoisomerase I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
PSF/p54(nrb) stimulates "jumping" of DNA topoisomerase I between separate DNA helices
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
A model for the mechanism of human topoisomerase I
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
The domain organization of human topoisomerase I
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
Biochemical and biophysical analyses of recombinant forms of human topoisomerase I
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
Identification of a nucleolin binding site in human topoisomerase I
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
16 March 2017
High mobility of proteins in the mammalian cell nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
7 April 2017
The N-terminal domain anchors human topoisomerase I at fibrillar centers of nucleoli and nucleolar organizer regions of mitotic chromosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Changes in mobility account for camptothecin-induced subnuclear relocation of topoisomerase I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Topoisomerase I-mediated DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Stabilized, long-term expression of heterodimeric proteins from tricistronic mRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
p53 dependence of topoisomerase I recruitment in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Expression, purification and DNA-cleavage activity of recombinant 68-kDa human topoisomerase I-target for antitumor drugs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Characterization of topotecan-mediated redistribution of DNA topoisomerase I by digital imaging microscopy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
In vivo sequencing of camptothecin-induced topoisomerase I cleavage sites in human colon carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Subcellular redistribution of DNA topoisomerase I in anaplastic astrocytoma cells treated with topotecan
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Studies on the role of topoisomerases in general, gene- and strand-specific DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Phosphorylation of DNA topoisomerase I is increased during the response of mammalian cells to mitogenic stimuli
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Eukaryotic DNA topoisomerases I.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
DNA topoisomerase poisons as antitumor drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Phosphorylation of mammalian DNA topoisomerase I and activation by protein kinase C.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
3 June 2018
Residues within the N-terminal Domain of Human Topoisomerase I Play a Direct Role in Relaxation*
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
26 November 2018
Modulation of DNA Topoisomerase I Activity byp53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
26 November 2018
Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispensable for catalytic activity but essential for in vivo function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291868
retrieved
26 November 2018
Functional expression of human DNA topoisomerase I and its subcellular localization in HeLa cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14654701
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Reconstitution of enzymatic activity by the association of the cap and catalytic domains of human topoisomerase I
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14654701
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14654701
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14654701
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DNA recombinase activity of eukaryotic DNA topoisomerase I; effects of camptothecin and other inhibitors
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14654701
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Human DNA topoisomerase I-mediated cleavages stimulated by ultraviolet light-induced DNA damage
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14654701
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Structural insights into the function of type IB topoisomerases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14654701
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Camptothecin-stabilised topoisomerase I-DNA complexes in leukaemia cells visualised and quantified in situ by the TARDIS assay (trapped in agarose DNA immunostaining)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/14654701
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/NAR/GKG927
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4280759
OpenCitations bibliographic resource ID
4280759
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4280759
PMCID
291868
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4280759
PubMed ID
14654701
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4280759
ResearchGate publication ID
277484896
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