(Q43172128)

15 November 2017

title

Model analysis of the concentration-dependent permeability of P-gp substrates (English)

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15 November 2017

Tatsuhiko Tachibana

1

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15 November 2017

Satoshi Kitamura

2

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15 November 2017

Motohiro Kato

3

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15 November 2017

Tetsuya Mitsui

4

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15 November 2017

Yoshiyuki Shirasaka

5

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15 November 2017

Shinji Yamashita

6

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15 November 2017

Yuichi Sugiyama

7

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15 November 2017

publication date

5 February 2010

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15 November 2017

published in

Pharmaceutical Research

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15 November 2017

volume

27

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15 November 2017

issue

3

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15 November 2017

page(s)

442-446

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Pharmacokinetics of pafenolol after i.v. and oral administration of three separate doses of different strength to man.

15 November 2017

cites work

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12 December 2020

Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL

1 reference

12 December 2020

Effect of P-glycoprotein expression levels on the concentration-dependent permeability of drugs to the cell membrane

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12 December 2020

Scaling of in vitro membrane permeability to predict P-glycoprotein-mediated drug absorption in vivo

1 reference

12 December 2020

Decrease in intracellular concentration causes the shift in Km value of efflux pump substrates.

1 reference

12 December 2020

Enhanced oral bioavailability of paclitaxel by coadministration of the P-glycoprotein inhibitor KR30031.

1 reference

12 December 2020

Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers: concentration- and dose-dependent absorption in vitro and in vivo.

1 reference

12 December 2020

Celiprolol: pharmacokinetics and duration of pharmacodynamic activity

1 reference

12 December 2020

The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein

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12 December 2020

Importance of P-glycoprotein at blood-tissue barriers

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12 December 2020

P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs

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12 December 2020

Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?

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12 December 2020

Importance of P-glycoprotein for drug disposition in humans

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12 December 2020

Impact of drug transporter studies on drug discovery and development

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12 December 2020

Functional polymorphisms of the human multidrug resistance (MDR1) gene: correlation with P glycoprotein expression and activity in vivo.

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12 December 2020

10.1007/S11095-009-0026-9

Identifiers

DOI

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15 November 2017

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