(Q43178842)

English

The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining

scientific article published on 18 September 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

The human set and transposase domain protein Metnase interacts with DNA Ligase IV and enhances the efficiency and accuracy of non-homologous end-joining (English)

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

author name string

Robert Hromas

1

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Justin Wray

2

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Suk-Hee Lee

3

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Leah Martinez

4

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Jacqueline Farrington

5

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Lori Kwan Corwin

6

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Heather Ramsey

7

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Jac A Nickoloff

8

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

Elizabeth A Williamson

9

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

publication date

18 September 2008

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

7

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

12

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

1927-1937

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2644637/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Human Pso4 is a metnase (SETMAR)-binding partner that regulates metnase function in DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

The endless tale of non-homologous end-joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Regulation of DNA double-strand break repair pathway choice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Biochemical characterization of a SET and transposase fusion protein, Metnase: its DNA binding and DNA cleavage activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

The ancient mariner sails again: transposition of the human Hsmar1 element by a reconstructed transposase and activities of the SETMAR protein on transposon ends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Functions and regulation of human artemis in double strand break repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

The human SETMAR protein preserves most of the activities of the ancestral Hsmar1 transposase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Birth of a chimeric primate gene by capture of the transposase gene from a mobile element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

A model of oncogenic rearrangements: differences between chromosomal translocation mechanisms and simple double-strand break repair

1 reference

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25 May 2018

Modulation of DNA end joining by nuclear proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

In vivo formation and repair of DNA double-strand breaks after computed tomography examinations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

1 reference

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25 May 2018

The BRCA2-interacting protein BCCIP functions in RAD51 and BRCA2 focus formation and homologous recombinational repair

1 reference

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25 May 2018

The life and death of DNA-PK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

MRE11/RAD50/NBS1: complex activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Repair of DNA double strand breaks by non-homologous end joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

The MRN complex: coordinating and mediating the response to broken chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Characteristics of gamma-H2AX foci at DNA double-strand breaks sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Impact of DNA ligase IV on the fidelity of end joining in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Initial sequencing and analysis of the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

A mechanistic basis for Mre11-directed DNA joining at microhomologies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

25 May 2018

Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

15 August 2018

End-joining of blunt DNA double-strand breaks in mammalian fibroblasts is precise and requires DNA-PK and XRCC4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

15 August 2018

The mutagenic potential of a single DNA double-strand break in a mammalian chromosome is not influenced by transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

15 August 2018

Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

15 August 2018

Breast cancer risk associated with genotypic polymorphism of the nonhomologous end-joining genes: a multigenic study on cancer susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

15 August 2018

The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2644637

15 August 2018

The DNA-dependent protein kinase catalytic activity regulates DNA end processing by means of Ku entry into DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/18773976

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High G/C content of cohesive overhangs renders DNA end joining Ku-independent

1 reference

https://pubmed.ncbi.nlm.nih.gov/18773976

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/18773976

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interplay between Ku, Artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends

1 reference

https://pubmed.ncbi.nlm.nih.gov/18773976

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

X-irradiation of cells on glass slides has a dose doubling impact

1 reference

https://pubmed.ncbi.nlm.nih.gov/18773976

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.DNAREP.2008.08.002

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 November 2017

ResearchGate publication ID

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