(Q35980970)

11 August 2017

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title

The life and death of DNA-PK. (English)

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11 August 2017

Spencer J Collis

1

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author name string

Theodore L DeWeese

series ordinal

2

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11 August 2017

Penelope A Jeggo

series ordinal

3

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11 August 2017

Antony R Parker

series ordinal

4

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11 August 2017

language of work or name

English

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publication date

1 February 2005

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11 August 2017

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11 August 2017

24

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11 August 2017

949-961

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11 August 2017

6

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208332

11 August 2017

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cites work

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The kinase activity of DNA-PK is required to protect mammalian telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Dysfunctional mammalian telomeres join with DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

c-Jun is phosphorylated by the DNA-dependent protein kinase in vitro; definition of the minimal kinase recognition motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The mechanism and regulation of chromosomal V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The C-terminal conserved domain of DNA-PKcs, missing in the SCID mouse, is required for kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Phosphatidyl inositol 3-kinase-like serine/threonine protein kinases (PIKKs) are required for DNA damage-induced phosphorylation of the 32 kDa subunit of replication protein A at threonine 21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Mechanisms of enhancement of cytotoxicity in etoposide and ionising radiation-treated cells by the protein kinase inhibitor wortmannin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Role of DNA-PK in the cellular response to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The Mre11 complex is required for ATM activation and the G2/M checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

A DNA-activated protein kinase from HeLa cell nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Mechanisms of chromosome-end protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Phosphorylation of human general transcription factors TATA-binding protein and transcription factor IIB by DNA-dependent protein kinase--synergistic stimulation of RNA polymerase II basal transcription in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Double strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Protection of mammalian telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Synapsis of DNA ends by DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Protein phosphatases regulate DNA-dependent protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Vanillins--a novel family of DNA-PK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Double-strand breaks and translocations in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Functional interaction between DNA-PKcs and telomerase in telomere length maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Mechanistic constraints on diversity in human V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Mapping of protein-protein interactions within the DNA-dependent protein kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-PKcs is critical for telomere capping

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

End-joining of free radical-mediated DNA double-strand breaks in vitro is blocked by the kinase inhibitor wortmannin at a step preceding removal of damaged 3' termini

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Radiation sensitization of human cancer cells in vivo by inhibiting the activity of PI3K using LY294002.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Partners and pathwaysrepairing a double-strand break.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Characterization of a Ku86 variant protein that results in altered DNA binding and diminished DNA-dependent protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-PK: the major target for wortmannin-mediated radiosensitization by the inhibition of DSB repair via NHEJ pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

RecQ helicases: caretakers of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Genome maintenance mechanisms for preventing cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

2,6-disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-Dependent protein kinase (DNA-PK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Complementation of the radiosensitive M059J cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Defining interactions between DNA-PK and ligase IV/XRCC4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Heat shock transcription factor 1 binds selectively in vitro to Ku protein and the catalytic subunit of the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-activated protein kinase in Raji Burkitt's lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA double strand break repair in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Functional interaction between DNA-PK and c-Abl in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

A targeted inhibition of DNA-dependent protein kinase sensitizes breast cancer cells following ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

NBS1 and its functional role in the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-dependent protein kinase specifically represses promoter-directed transcription initiation by RNA polymerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Repair of DNA double strand breaks by non-homologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Genetic instabilities in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Structure of DNA-dependent protein kinase: implications for its regulation by DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Modification of the ionizing radiation response in living cells by an scFv against the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Mechanism and regulation of human non-homologous DNA end-joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Electron microscopy studies on DNA recognition by DNA-PK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

MDC1 regulates DNA-PK autophosphorylation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Association of terminal deoxynucleotidyl transferase with Ku

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

A Ku80 fragment with dominant negative activity imparts a radiosensitive phenotype to CHO-K1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Transfer of Ku86 RNA antisense decreases the radioresistance of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Targeting tumor cells by enhancing radiation sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Molecular genetic characterization of XRCC4 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

KARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Cellular responses to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Suppression of a DNA double-strand break repair gene, Ku70, increases radio- and chemosensitivity in a human lung carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Utilization of oriented peptide libraries to identify substrate motifs selected by ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Chromosomal end-to-end fusions in immortalized mouse embryonic fibroblasts deficient in the DNA-dependent protein kinase catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Stimulation of the DNA-dependent protein kinase by poly(ADP-ribose) polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Up‐regulation of DNA‐dependent protein kinase correlates with radiation resistance in oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-dependent protein kinase content and activity in lung carcinoma cell lines: correlation with intrinsic radiosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Prospects for phosphoinositide 3-kinase inhibition as a cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Synthesis, crystal structure determination, and biological properties of the DNA-dependent protein kinase (DNA-PK) inhibitor 3-cyano-6-hydrazonomethyl-5-(4-pyridyl)pyrid-[1H]-2-one (OK-1035).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Recombinational DNA repair and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Requirement of the MRN complex for ATM activation by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Decreased DNA-PK activity in human cancer cells exhibiting hypersensitivity to low-dose irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Regulation and mechanisms of mammalian double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Chromosomal stability and the DNA double-stranded break connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-PKcs function regulated specifically by protein phosphatase 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Expression of Ku70 correlates with survival in carcinoma of the cervix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Isolation of Ku70-binding proteins (KUBs)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

ATM, ATR and DNA-PK: initiators of the cellular genotoxic stress responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

V(D)J rearrangement in Nijmegen breakage syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

High mobility group proteins 1 and 2 can function as DNA-binding regulatory components for DNA-dependent protein kinase in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

The DNA-dependent protein kinase catalytic activity regulates DNA end processing by means of Ku entry into DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

Expression of the DNA-PK binding protein E4-34K fails to confer radiation sensitivity to mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

The Greek Goddess, Artemis, reveals the secrets of her cleavage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

Evidence for the involvement of DNA-dependent protein kinase in the phenomena of low dose hyper-radiosensitivity and increased radioresistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

Regulation of DNA-dependent protein kinase activity in leukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

Stimulation of the DNA-dependent protein kinase by RNA polymerase II transcriptional activator proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

OK-1035, a selective inhibitor of DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

Stimulation of DNA-dependent protein kinase activity by high mobility group proteins 1 and 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

SLAM (CDw150) is a cellular receptor for measles virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208332

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208332

1 reference

Dimensions Publication ID

11 August 2017

0 references

1 reference