(Q77398644)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9768756%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

title

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9768756%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

author name string

Y Gao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9768756%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

J Chaudhuri

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9768756%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

C Zhu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9768756%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

L Davidson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9768756%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

D T Weaver

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9768756%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

F W Alt

6

1 reference

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5 December 2019

publication date

1 September 1998

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5 December 2019

1 reference

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5 December 2019

volume

9

1 reference

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5 December 2019

issue

3

1 reference

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5 December 2019

page(s)

367-376

1 reference

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Intact G2-phase checkpoint in cells of a human cell line lacking DNA-dependent protein kinase activity.

5 December 2019

cites work

1 reference

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7 January 2021

scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair

1 reference

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7 January 2021

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

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7 January 2021

A severe combined immunodeficiency mutation in the mouse

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7 January 2021

Evidence of functional lymphocytes in some (leaky) scid mice

1 reference

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7 January 2021

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

1 reference

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7 January 2021

A DNA-activated protein kinase from HeLa cell nuclei

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7 January 2021

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

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7 January 2021

Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

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7 January 2021

The murine DNA-PKcs gene consists of 86 exons dispersed in more than 250 kb.

1 reference

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7 January 2021

Murine cell line SX9 bearing a mutation in the dna-pkcs gene exhibits aberrant V(D)J recombination not only in the coding joint but also in the signal joint

1 reference

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7 January 2021

The scid mutation in mice causes a general defect in DNA repair

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7 January 2021

V(D)J recombination gets a break

1 reference

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7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

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7 January 2021

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

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7 January 2021

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

1 reference

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7 January 2021

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

1 reference

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7 January 2021

DNA-dependent protein kinase: DNA binding and activation in the absence of Ku

1 reference

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7 January 2021

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

1 reference

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7 January 2021

The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement

1 reference

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7 January 2021

A link between double-strand break-related repair and V(D)J recombination: the scid mutation

1 reference

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7 January 2021

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

1 reference

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7 January 2021

DNA-PK: at the cross-roads of biochemistry and genetics

1 reference

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7 January 2021

DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus

1 reference

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7 January 2021

Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

1 reference

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7 January 2021

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

1 reference

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7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

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7 January 2021

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1 reference

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7 January 2021

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

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7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

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7 January 2021

Involvement of Brca2 in DNA repair

1 reference

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7 January 2021

V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair

1 reference

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7 January 2021

Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

1 reference

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7 January 2021

Characterization of two DNA double-stranded break repair-deficient cell lines that express inactive DNA-dependent protein kinase catalytic subunits

1 reference

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7 January 2021

Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

1 reference

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7 January 2021

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Characterization of broken DNA molecules associated with V(D)J recombination

1 reference

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7 January 2021

The V(D)J recombination activating gene, RAG-1.

1 reference

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7 January 2021

Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA.

1 reference

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7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

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7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

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7 January 2021

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

What to do at an end: DNA double-strand-break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Characterization of coding ends in thymocytes of scid mice: Implications for the mechanism of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980619-6

7 January 2021

10.1016/S1074-7613(00)80619-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9768756%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference