(Q52191949)

26 April 2018

title

Growth retardation and leaky SCID phenotype of Ku70-deficient mice. (English)

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26 April 2018

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9

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26 April 2018

author name string

Y Gu

1

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26 April 2018

K J Seidl

2

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26 April 2018

G A Rathbun

3

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26 April 2018

C Zhu

4

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26 April 2018

J P Manis

5

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26 April 2018

N van der Stoep

6

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26 April 2018

L Davidson

7

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26 April 2018

H L Cheng

8

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26 April 2018

K Frank

10

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26 April 2018

P Stanhope-Baker

11

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26 April 2018

M S Schlissel

12

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26 April 2018

D B Roth

13

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26 April 2018

F W Alt

14

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26 April 2018

language of work or name

English

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publication date

1 November 1997

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26 April 2018

published in

Immunity

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26 April 2018

volume

7

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26 April 2018

page(s)

653-665

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26 April 2018

issue

5

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26 April 2018

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

V(D)J recombination in Ku86-deficient mice: distinct effects on coding, signal, and hybrid joint formation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

A severe combined immunodeficiency mutation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Complementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Development of B cells in scid mice with immunoglobulin transgenes: implications for the control of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Normal recombination substrate VH to DJH rearrangements in pre-B cell lines from scid mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Mice lacking TdT: mature animals with an immature lymphocyte repertoire

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Ku86 is not required for protection of signal ends or for formation of nonstandard V(D)J recombination products

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Wild-type V(D)J recombination in scid pre-B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Functional interaction between DNA-PK and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

The V(D)J recombination defect in the xrs-6 cell line results from a point mutation in the Ku80 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

A DNA end-binding factor involved in double-strand break repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Characterization of broken DNA molecules associated with V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Clustered illegitimate recombination events in mammalian cells involving very short sequence homologies

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

The V(D)J recombination activating gene, RAG-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Frequent occurrence of identical heavy and light chain Ig rearrangements

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Molecular and biochemical characterization of xrs mutants defective in Ku80.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Replicative senescence: implications for in vivo aging and tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

B cell development under the condition of allelic inclusion.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Impairment of V(D)J recombination in double-strand break repair mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Initiation of V(D)J recombination in a cell-free system.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Equine severe combined immunodeficiency: a defect in V(D)J recombination and DNA-dependent protein kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Developmental regulation of V(D)J recombination and lymphocyte differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Yeast DNA ligase IV mediates non-homologous DNA end joining

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Characterization of coding ends in thymocytes of scid mice: implications for the mechanism of V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980386-6

7 January 2021

10.1016/S1074-7613(00)80386-6

Identifiers

DOI

1 reference

26 April 2018

PubMed ID

9390689

1 reference

26 April 2018