(Q28214575)

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Partners and pathwaysrepairing a double-strand break.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Non-homologous end joining as a mechanism of DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

NHEJ deficiency and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Homologous recombinational repair of DNA ensures mammalian chromosome stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA double-strand breaks: signaling, repair and the cancer connection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Sensing and repairing DNA double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA double strand break repair and chromosomal translocation: lessons from animal models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The inherited basis of human radiosensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA-PKcs is critical for telomere capping

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

How to make ends meet in V(D)J recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The contribution of homologous recombination in preserving genome integrity in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The role of homologous recombination processes in the repair of severe forms of DNA damage in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM: genome stability, neuronal development, and cancer cross paths

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM, a central controller of cellular responses to DNA damage.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM function and telomere stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Inherited sensitivity to X-rays in man.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Cloning Efficiency and Spontaneous Mutant Frequency in Circulating T-lymphocytes in Ataxia-telangiectasia Patients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

On the nature of a defect in cells from individuals with ataxia-telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Relationship of the ataxia-telangiectasia protein ATM to phosphoinositide 3-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Localization of a portion of extranuclear ATM to peroxisomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM: a mediator of multiple responses to genotoxic stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM and ATR: networking cellular responses to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

MKP5, a new member of the MAP kinase phosphatase family, which selectively dephosphorylates stress-activated kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Schizosaccharomyces pombe rad3 checkpoint gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Cell cycle checkpoint signaling through the ATM and ATR kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Megabase chromatin domains involved in DNA double-strand breaks in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Enhanced phosphorylation of p53 by ATM in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Genomic instability in mice lacking histone H2AX

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The controlling role of ATM in homologous recombinational repair of DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Atm-deficient mice: a paradigm of ataxia telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Atm haploinsufficiency results in increased sensitivity to sublethal doses of ionizing radiation in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Regulation of Rad51 function by c-Abl in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

c-Abl tyrosine kinase is not essential for ataxia telangiectasia mutated functions in chromosomal maintenance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Cancer risk and the ATM gene: a continuing debate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Public health burden of cancer in ataxia-telangiectasia heterozygotes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Dominant Negative ATM Mutations in Breast Cancer Families

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Radiosensitivity of ataxia telangiectasia and Nijmegen breakage syndrome homozygotes and heterozygotes as determined by three-color FISH chromosome painting

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A new chromosomal instability disorder: the Nijmegen breakage syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Positional cloning of the gene for Nijmegen breakage syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Nijmegen breakage syndrome: consequences of defective DNA double strand break repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Cell cycle checkpoints and DNA repair in Nijmegen breakage syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Radiation induction of p53 in cells from Nijmegen breakage syndrome is defective but not similar to ataxia-telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Impaired p53-mediated DNA damage response, cell-cycle disturbance and chromosome aberrations in Nijmegen breakage syndrome lymphoblastoid cell lines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Chk2 activation dependence on Nbs1 after DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Expression of full-length NBS1 protein restores normal radiation responses in cells from Nijmegen breakage syndrome patients.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Decreased immunoglobulin class switching in Nijmegen Breakage syndrome due to the DNA repair defect.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

In situ visualization of DNA double-strand break repair in human fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA damage-dependent nuclear dynamics of the Mre11 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM-dependent phosphorylation of nibrin in response to radiation exposure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A murine model of Nijmegen breakage syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

No evidence for deletions of the NBS1 gene in lymphomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Mre11 complex and ATM: collaborating to navigate S phase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA helicases, genomic instability, and human genetic disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Elevated spontaneous mutation rate in Bloom syndrome fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Evidence for increased in vivo mutation and somatic recombination in Bloom's syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Bloom's syndrome gene product is homologous to RecQ helicases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

RecQ family helicases: roles in cancer and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Regulation and localization of the Bloom syndrome protein in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM-dependent phosphorylation and accumulation of endogenous BLM protein in response to ionizing radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Possible association of BLM in decreasing DNA double strand breaks during DNA replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Functional interaction of p53 and BLM DNA helicase in apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Bloom syndrome protein interacts and cooperates with p53 in regulation of transcription and cell growth control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Selective cleavage of BLM, the bloom syndrome protein, during apoptotic cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Unwinding the molecular basis of the Werner syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Werner and Bloom helicases are involved in DNA repair in a complementary fashion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Werner's syndrome cell lines are hypersensitive to camptothecin-induced chromosomal damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Positional cloning of the Werner's syndrome gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Characterization of the human and mouse WRN 3'-->5' exonuclease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

WRN helicase expression in Werner syndrome cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mutations in the WRN gene in mice accelerate mortality in a p53-null background

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Roles of the Werner syndrome protein in pathways required for maintenance of genome stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Loss of Werner syndrome protein function promotes aberrant mitotic recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Homologous recombination resolution defect in werner syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Rothmund-Thomson syndrome due to RECQ4 helicase mutations: report and clinical and molecular comparisons with Bloom syndrome and Werner syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Rothmund-thomson syndrome responsible gene, RECQL4: genomic structure and products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Is Fanconi anemia caused by a defect in the processing of DNA damage?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Fanconi anemia and DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The emerging genetic and molecular basis of Fanconi anaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Current knowledge on the pathophysiology of Fanconi anemia: from genes to phenotypes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mice with a targeted disruption of the Fanconi anemia homolog Fanca

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Fanconi anemia group A and C double-mutant mice: functional evidence for a multi-protein Fanconi anemia complex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Reduced fertility and hypersensitivity to mitomycin C characterize Fancg/Xrcc9 null mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Fanconi anaemia proteins, FAA and FAC, interact to form a nuclear complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

FANCE: the link between Fanconi anaemia complex assembly and activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The two faces of BRCA2, a FANCtastic discovery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Biallelic inactivation of BRCA2 in Fanconi anemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Breast cancer genetics: what we know and what we need

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 required for transcription-coupled repair of oxidative DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Lessons learned from BRCA1 and BRCA2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Insights into the functions of BRCA1 and BRCA2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

In search of the tumour-suppressor functions of BRCA1 and BRCA2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

New complexities for BRCA1 and BRCA2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Distinct functions of BRCA1 and BRCA2 in double-strand break repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Cancer susceptibility and the functions of BRCA1 and BRCA2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Brca1 controls homology-directed DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Direct DNA binding by Brca1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 facilitates microhomology-mediated end joining of DNA double strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The human decatenation checkpoint.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 is associated with the centrosome during mitosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Redistribution of BRCA1 among four different protein complexes following replication blockage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Independence of R/M/N focus formation and the presence of intact BRCA1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Identification of residues required for the interaction of BARD1 with BRCA1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The cancer-predisposing mutation C61G disrupts homodimer formation in the NH2-terminal BRCA1 RING finger domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 RING domain cancer-predisposing mutations. Structural consequences and effects on protein-protein interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 is a component of the RNA polymerase II holoenzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 physically and functionally interacts with ATF1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The BRCA1 C-terminal domain: structure and function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 interacts with components of the histone deacetylase complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

CBP/p300 interact with and function as transcriptional coactivators of BRCA1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The BRCA2 gene product functionally interacts with p53 and RAD51

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Internal repeats in the BRCA2 protein sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The BRC repeats are conserved in mammalian BRCA2 proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Involvement of Brca2 in DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Structural analysis of the chicken BRCA2 gene facilitates identification of functional domains and disease causing mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Changes in BRCA2 expression during progression of the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mitotic checkpoint inactivation fosters transformation in cells lacking the breast cancer susceptibility gene, Brca2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mammalian recombination-repair genes XRCC2 and XRCC3 promote correct chromosome segregation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The Rad51 paralog Rad51B promotes homologous recombinational repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Chromosomal instability in BRCA1- or BRCA2-defective human cancer cells detected by spontaneous micronucleus assay.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Impaired DNA damage-induced nuclear Rad51 foci formation uniquely characterizes Fanconi anemia group D1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA2 is required for homology-directed repair of chromosomal breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Conserved domains in the chicken homologue of BRCA2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Transcriptional activation functions in BRCA2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA2 associates with acetyltransferase activity when bound to P/CAF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Inhibition of breast and brain cancer cell growth by BCCIPalpha, an evolutionarily conserved nuclear protein that interacts with BRCA2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Synergistic actions of Rad51 and Rad52 in recombination and DNA repair.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Homologous pairing promoted by the human Rad52 protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Human Rad54B is a double-stranded DNA-dependent ATPase and has biochemical properties different from its structural homolog in yeast, Tid1/Rdh54

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A role for RAD54B in homologous recombination in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A novel human rad54 homologue, Rad54B, associates with Rad51

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Double-strand breaks and tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Abnormal expression of BRCA1 and BRCA1-interactive DNA-repair proteins in breast carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

RAD51 supports spontaneous non-homologous recombination in mammalian cells, but not the corresponding process induced by topoisomerase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Effects of HsRad51 overexpression on cell proliferation, cell cycle progression, and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Role of mammalian RAD51L2 (RAD51C) in recombination and genetic stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Identification and purification of two distinct complexes containing the five RAD51 paralogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Evidence for RAD51L1/HMGIC fusion in the pathogenesis of uterine leiomyoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Cumulative dosage effect of a RAD51L1/HMGA2 fusion and RAD51L1 loss in a case of pseudo-Meigs' syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA repair gene polymorphisms, bulky DNA adducts in white blood cells and bladder cancer in a case-control study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Variants in DNA double-strand break repair genes and breast cancer susceptibility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Genetic polymorphisms in DNA repair genes and risk of lung cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair and breast cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

hRAD30 mutations in the variant form of xeroderma pigmentosum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Post-translational modifications and activation of p53 by genotoxic stresses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Protective role for c-Jun in the cellular response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The BRCA1 suppressor hypothesis: An explanation for the tissue-specific tumor development in BRCA1 patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The hCds1 (Chk2)-FHA domain is essential for a chain of phosphorylation events on hCds1 that is induced by ionizing radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM associates with and phosphorylates p53: mapping the region of interaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Interaction between ATM protein and c-Abl in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Chk2 activation and phosphorylation-dependent oligomerization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1-associated growth arrest is RB-dependent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 regulates p53-dependent gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900224-5

10.1016/S0027-5107(02)00224-5

7 January 2021

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12427531

1 reference

Consolidated OpenCitations Corpus – April 2017