(Q28206293)

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Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation

scientific article (publication date: 24 May 2002)

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11889123%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11889123%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

phosphorylation

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based on heuristic

inferred from title

8

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8 December 2019

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Parimal Karmakar

1

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8 December 2019

Jason Piotrowski

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11889123%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Robert M Brosh

3

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8 December 2019

Joshua A Sommers

4

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8 December 2019

Susan P Lees Miller

5

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8 December 2019

Wen-Hsing Cheng

6

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8 December 2019

Carey M Snowden

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11889123%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Vilhelm A Bohr

9

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8 December 2019

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publication date

11 March 2002

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8 December 2019

number of pages

12

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Journal of Biological Chemistry

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8 December 2019

277

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8 December 2019

21

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8 December 2019

18291-18302

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Europe PubMed Central

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8 December 2019

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Positional cloning of the Werner's syndrome gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

The Werner syndrome protein is a DNA helicase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Mutator phenotype of Werner syndrome is characterized by extensive deletions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Ku, a DNA repair protein with multiple cellular functions?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Deletion of Ku86 causes early onset of senescence in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Hypersensitivity of Ku80-deficient cell lines and mice to DNA damage: the effects of ionizing radiation on growth, survival, and development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

The DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Ku recruits the XRCC4-ligase IV complex to DNA ends

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Mapping of protein-protein interactions within the DNA-dependent protein kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Protein phosphatases regulate DNA-dependent protein kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Functional and physical interaction between WRN helicase and human replication protein A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Human TP53 from the malignant glioma-derived cell lines M059J and M059K has a cancer-associated mutation in exon 8.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Werner syndrome protein: biochemical properties and functional interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Spontaneous and X-ray-induced chromosomal aberrations in Werner syndrome cells detected by FISH using chromosome-specific painting probes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Lack of correlation between ATM protein expression and tumour cell radiosensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Molecular and biochemical characterization of xrs mutants defective in Ku80.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

The Werner syndrome protein is involved in RNA polymerase II transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

p53-mediated apoptosis is attenuated in Werner syndrome cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Phosphorylation of simian virus 40 T antigen on Thr 124 selectively promotes double-hexamer formation on subfragments of the viral core origin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Sequence-specific DNA binding by Ku autoantigen and its effects on transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111523200

21 January 2018

Identifiers

10.1074/JBC.M111523200

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11889123%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11889123%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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