(Q53397555)

13 May 2018

title

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. (English)

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13 May 2018

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Xu X

1

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13 May 2018

Qiao W

2

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13 May 2018

Linke SP

3

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13 May 2018

Cao L

4

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13 May 2018

Li WM

5

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13 May 2018

Furth PA

6

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13 May 2018

Harris CC

7

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13 May 2018

Deng CX

8

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13 May 2018

language of work or name

English

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publication date

1 July 2001

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13 May 2018

published in

Nature Genetics

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13 May 2018

volume

28

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13 May 2018

issue

3

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13 May 2018

page(s)

266-271

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/90108

exact match

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cites work

Hereditary breast cancer

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7 January 2021

The BRCA1 and BRCA2 breast cancer genes.

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7 January 2021

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

1 reference

7 January 2021

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

1 reference

7 January 2021

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

1 reference

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

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7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

1 reference

7 January 2021

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

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7 January 2021

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

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7 January 2021

A subset of p53-deficient embryos exhibit exencephaly

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7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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7 January 2021

Twenty years of p53 research: structural and functional aspects of the p53 protein

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7 January 2021

Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents

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7 January 2021

Repression of BRCA1 through a feedback loop involving p53.

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

Phosphorylation sites in the amino-terminal region of mouse p53

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7 January 2021

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

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7 January 2021

Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks

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7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

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7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

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7 January 2021

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

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7 January 2021

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

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7 January 2021

Growth retardation, DNA repair defects, and lack of spermatogenesis in BRCA1-deficient mice

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7 January 2021

Is TP53 dysfunction required for BRCA1-associated carcinogenesis?

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7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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7 January 2021

Identifiers

DOI

10.1038/90108

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13 May 2018

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13 May 2018