(Q42490218)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10884389%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

Repression of BRCA1 through a feedback loop involving p53 (English)

1 reference

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8 November 2019

4

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8 November 2019

author name string

MacLachlan TK

series ordinal

1

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8 November 2019

Dash BC

series ordinal

2

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8 November 2019

Dicker DT

series ordinal

3

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8 November 2019

language of work or name

English

0 references

publication date

1 October 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10884389%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

8 November 2019

published in

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8 November 2019

volume

275

1 reference

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8 November 2019

issue

41

1 reference

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8 November 2019

page(s)

31869-31875

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The functions of breast cancer susceptibility gene 1 (BRCA1) product and its associated proteins

8 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Association of BRCA1 with Rad51 in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 is a component of the RNA polymerase II holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 interacts with components of the histone deacetylase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 required for transcription-coupled repair of oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 regulates p53-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 signals ARF-dependent stabilization and coactivation of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Down-regulation of BRCA1 and BRCA2 in human ovarian cancer cells exposed to adriamycin and ultraviolet radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Localization of BRCA1 and a splice variant identifies the nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Distinct roles for cyclin-dependent kinases in cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Positive regulation of the BRCA1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Regulation of BRCA1 by protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Genetic analysis of BRCA1 function in a defined tumor cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003338200

21 January 2018

Identifiers

DOI

10.1074/JBC.M003338200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10884389%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference