(Q43179699)

15 November 2017

The isolated rabbit heart and Purkinje fibers as models for identifying proarrhythmic liability (English)

1 reference

15 November 2017

Michel Roche

1

1 reference

15 November 2017

Céline Renauleaud

2

1 reference

15 November 2017

Véronique Ballet

3

1 reference

15 November 2017

Michel Doubovetzky

4

1 reference

15 November 2017

Jean-Michel Guillon

5

1 reference

15 November 2017

1 February 2010

1 reference

Journal of Pharmacological and Toxicological Methods

15 November 2017

1 reference

15 November 2017

61

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15 November 2017

3

1 reference

15 November 2017

238-250

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Dofetilide-induced long QT and torsades de pointes.

15 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

The pharmacokinetics and pharmacodynamics of oral dofetilide after twice daily and three times daily dosing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Arrhythmogenic mechanisms of QT prolonging drugs: is QT prolongation really the problem?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Heterogeneity and cardiac arrhythmias: an overview.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Transmural dispersion of repolarization and arrhythmogenicity: the Brugada syndrome versus the long QT syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Evaluation of the rabbit Purkinje fibre assay as an in vitro tool for assessing the risk of drug-induced torsades de pointes in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Assessing predictors of drug-induced torsade de pointes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Use of arterially perfused rabbit ventricular wedge in predicting arrhythmogenic potentials of drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Models of torsades de pointes: effects of FPL64176, DPI201106, dofetilide, and chromanol 293B in isolated rabbit and guinea pig hearts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Isolated perfused and paced guinea pig heart to test for drug-induced changes of the QT interval

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Influence of dofetilide on QT-interval duration and dispersion at various heart rates during exercise in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Electrophysiological mechanism of the characteristic electrocardiographic morphology of torsade de pointes tachyarrhythmias in the long-QT syndrome: detailed analysis of ventricular tridimensional activation patterns

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Epicardial activation of left ventricular wall prolongs QT interval and transmural dispersion of repolarization: implications for biventricular pacing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

L-type calcium current recovery versus ventricular repolarization: preserved membrane-stabilizing mechanism for different QT intervals across species

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Drug-induced torsades de pointes: role of early afterdepolarizations and dispersion of repolarization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

What is a monophasic action potential?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Cellular basis for the monophasic action potential. Which electrode is the recording electrode?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

A rabbit Langendorff heart proarrhythmia model: predictive value for clinical identification of Torsades de Pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Pharmacokinetic and pharmacodynamic modeling of the effects of oral and intravenous administrations of dofetilide on ventricular repolarization*

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Sex modulates the arrhythmogenic substrate in prepubertal rabbit hearts with Long QT 2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Drug-induced long QT in isolated rabbit Purkinje fibers: importance of action potential duration, triangulation and early afterdepolarizations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Proarrhythmia as a class effect of quinolones: increased dispersion of repolarization and triangulation of action potential predict torsades de pointes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Principles of safety pharmacology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Sex, age, and regional differences in L-type calcium current are important determinants of arrhythmia phenotype in rabbit hearts with drug-induced long QT type 2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Impact of study design on proarrhythmia prediction in the SCREENIT rabbit isolated heart model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Dofetilide in patients with congestive heart failure and left ventricular dysfunction. Danish Investigations of Arrhythmia and Mortality on Dofetilide Study Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Ventricular repolarization components on the electrocardiogram: cellular basis and clinical significance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Modulating effects of age and gender on the clinical course of long QT syndrome by genotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

Detection of proarrhythmia in the female rabbit heart: blinded validation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VASCN.2010.01.011

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VASCN.2010.01.011

1 reference

15 November 2017

1 reference