(Q43184299)

15 November 2017

title

Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver (English)

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15 November 2017

main subject

hepatocellular carcinoma

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8

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15 November 2017

Y Wu

1

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15 November 2017

Y Y Wang

2

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15 November 2017

Y Nakamoto

3

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15 November 2017

Y-Y Li

4

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15 November 2017

T Baba

5

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15 November 2017

S Kaneko

6

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15 November 2017

C Fujii

7

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15 November 2017

language of work or name

English

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publication date

18 January 2010

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15 November 2017

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15 November 2017

volume

29

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15 November 2017

issue

15

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15 November 2017

page(s)

2228-2237

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The oncogenic serine/threonine kinase Pim-1 phosphorylates and inhibits the activity of Cdc25C-associated kinase 1 (C-TAK1): a novel role for Pim-1 at the G2/M cell cycle checkpoint

15 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Structure and substrate specificity of the Pim-1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Hepatocellular carcinoma pathogenesis: from genes to environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

KID-1, a protein kinase induced by depolarization in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Aberrant expression of serine/threonine kinase Pim-3 in hepatocellular carcinoma development and its role in the proliferation of human hepatoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Pim-3, a proto-oncogene with serine/threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates bad to block bad-mediated apoptosis in human pancreatic cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Expression of GCIP in transgenic mice decreases susceptibility to chemical hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Cytokines in non-genotoxic hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Mechanisms of Liver Injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Interaction of AP-1 with a cluster of NF-kappa B binding elements in the human TNF promoter region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Epidemiology of hepatocellular carcinoma in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts and promotes angiogenesis in murine lung metastasis process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Essential contribution of a chemokine, CCL3, and its receptor, CCR1, to hepatocellular carcinoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxel-treated prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Aberrant Pim-3 expression is involved in gastric adenoma-adenocarcinoma sequence and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

1,25(OH)(2)D(3) blocks TNF-induced monocytic tissue factor expression by inhibition of transcription factors AP-1 and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Leflunomide suppresses TNF-induced cellular responses: effects on NF-kappa B, activator protein-1, c-Jun N-terminal protein kinase, and apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

Molecular pathogenesis of human hepatocellular carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.504

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.504

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Dimensions Publication ID

15 November 2017

1028071049

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Fatcat ID

release_qbmkcy6rnbgqngceqgh2ek72vu

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Fatcat

https://api.fatcat.wiki/v0/release/qbmkcy6rnbgqngceqgh2ek72vu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference