(Q43187988)

English

In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death

scientific article published on 4 March 2008

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scholarly article

1 reference

Europe PubMed Central

15 November 2017

In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death (English)

1 reference

Europe PubMed Central

15 November 2017

Giles E. Hardingham

3

1 reference

Europe PubMed Central

15 November 2017

author name string

M-A Martel

1

1 reference

Europe PubMed Central

15 November 2017

D J A Wyllie

2

1 reference

Europe PubMed Central

15 November 2017

language of work or name

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publication date

4 March 2008

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Europe PubMed Central

15 November 2017

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Europe PubMed Central

15 November 2017

158

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Europe PubMed Central

15 November 2017

334-343

1 reference

Europe PubMed Central

15 November 2017

1

1 reference

Europe PubMed Central

15 November 2017

The dichotomy of NMDA receptor signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Involvement of NR2A- or NR2B-containing N-methyl-D-aspartate receptors in the potentiation of cortical layer 5 pyramidal neurone inputs depends on the developmental stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Taking the time to study competitive antagonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

The role of NMDAR subtypes and charge transfer during hippocampal LTP induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

NMDA receptor function: subunit composition versus spatial distribution

1 reference

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25 May 2018

The chemical biology of clinically tolerated NMDA receptor antagonists

1 reference

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25 May 2018

Equilibrium constants for (R)-[(S)-1-(4-bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic acid (NVP-AAM077) acting at recombinant NR1/NR2A and NR1/NR2B N-methyl-D-aspartate receptors: Implications for studies

1 reference

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25 May 2018

Survival signaling pathways activated by NMDA receptors

1 reference

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25 May 2018

Pharmacological insights obtained from structure-function studies of ionotropic glutamate receptors

1 reference

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25 May 2018

Glutamate-based therapeutic approaches: clinical trials with NMDA antagonists

1 reference

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25 May 2018

Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory

1 reference

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25 May 2018

Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Glutamate receptor gating.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Role of distinct NMDA receptor subtypes at central synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?

1 reference

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25 May 2018

The Yin and Yang of NMDA receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Aptiganel hydrochloride in acute ischemic stroke: a randomized controlled trial

1 reference

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25 May 2018

Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Neuroprotective concentrations of the N-methyl-D-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation.

1 reference

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25 May 2018

Developmental changes in NMDA receptor glycine affinity and ifenprodil sensitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons.

1 reference

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25 May 2018

Expression of mRNAs encoding subunits of the N-methyl-D-aspartate receptor in cultured cortical neurons.

1 reference

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25 May 2018

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

1 reference

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25 May 2018

Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

25 May 2018

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.

1 reference

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25 May 2018

Stimulation of Protein Tyrosine Phosphorylation by NMDA Receptor Activation

1 reference

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Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

1 reference

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15 August 2018

Extrasynaptic and synaptic NMDA receptors form stable and uniform pools in rat hippocampal slices.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2635533

15 August 2018

Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors.

1 reference

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15 August 2018

NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo.

1 reference

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Decoding NMDA receptor signaling: identification of genomic programs specifying neuronal survival and death.

1 reference

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Phosphatidylinositol 3 kinase activation and AMPA receptor subunit trafficking underlie the potentiation of miniature EPSC amplitudes triggered by the activation of L-type calcium channels.

1 reference

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Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the extracellular signal-regulated kinases (ERK) activity in cultured rat hippocampal neurons

1 reference

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15 August 2018

Relating NMDA receptor function to receptor subunit composition: limitations of the pharmacological approach.

1 reference

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15 August 2018

Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons

1 reference

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Nuclear Ca2+ and the cAMP response element-binding protein family mediate a late phase of activity-dependent neuroprotection.

1 reference

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Diminished neuronal activity increases neuron-neuron connectivity underlying silent synapse formation and the rapid conversion of silent to functional synapses.

1 reference

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Microelectrode array recordings of cultured hippocampal networks reveal a simple model for transcription and protein synthesis-dependent plasticity

1 reference

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15 August 2018

Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression.

1 reference

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15 August 2018

Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity

1 reference

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Epileptiform activity in rat hippocampus strengthens excitatory synapses

1 reference

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15 August 2018

Coupling of extrasynaptic NMDA receptors to a CREB shut-off pathway is developmentally regulated

1 reference

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15 August 2018

Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity.

1 reference

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Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal DNA cleavage: implications for programmed cell death mechanisms.

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Shakespeare in love--with NMDA receptors?

1 reference

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15 August 2018

Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons.

1 reference

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C-Terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18378405

12 December 2020

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10.1016/J.NEUROSCIENCE.2008.01.080

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Europe PubMed Central

15 November 2017

1 reference

Europe PubMed Central

15 November 2017

1 reference

Europe PubMed Central

15 November 2017

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