(Q43190608)

15 November 2017

Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity (English)

1 reference

15 November 2017

nitrososulfamethoxazole

1 reference

ChEBI release 2020-05-28

4

1 reference

15 November 2017

D J Naisbitt

1

1 reference

15 November 2017

S J Hough

2

1 reference

15 November 2017

H J Gill

3

1 reference

15 November 2017

N R Kitteringham

5

1 reference

15 November 2017

B K Park

6

1 reference

15 November 2017

language of work or name

English

0 references

publication date

1 March 1999

1 reference

British Journal of Pharmacology

15 November 2017

1 reference

15 November 2017

126

1 reference

15 November 2017

6

1 reference

15 November 2017

1393-1407

1 reference

Apoptosis and necrosis in toxicology: a continuum or distinct modes of cell death?

15 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Oxidative stress and thiol depletion in plasma and peripheral blood lymphocytes from HIV-infected patients: toxicological and pathological implications

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Acetaminophen-induced hepatotoxicity is associated with early changes in NF-kappa B and NF-IL6 DNA binding activity

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Disposition of amodiaquine and related antimalarial agents in human neutrophils: implications for drug design

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Adverse reactions to sulphonamide and sulphonamide-trimethoprim antimicrobials: clinical syndromes and pathogenesis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

The effect of fluconazole and ketoconazole on the metabolism of sulphamethoxazole

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Acetaminophen-induced hepatotoxicity is associated with early changes in AP-1 DNA binding activity

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

HIV-related skin diseases

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Differential distribution of free and bound glutathione and cyst(e)ine in human blood

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

In vitro cytotoxicity as a marker of hypersensitivity to sulphamethoxazole in patients with HIV.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Treatment of infections in the patient with acquired immunodeficiency syndrome

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Function and activation of NF-kappa B in the immune system

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Immunochemical analysis of sulfonamide drug allergy: identification of sulfamethoxazole-substituted human serum proteins

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Glucocorticoid treatment inhibits apoptosis in human neutrophils. Separation of survival and activation outcomes.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Immune response to sulfamethoxazole in patients with AIDS.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Purification and characterization of nitrobenzene nitroreductase from Pseudomonas pseudoalcaligenes JS45

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Investigations of glutathione conjugation in vitro by 1H NMR spectroscopy. Uncatalyzed and glutathione transferase-catalyzed reactions

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Pathogenesis and management of HIV-associated drug hypersensitivity.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Studies on the enzymatic reduction of C-nitroso compounds. IV. Partial purification and kinetic properties of porcine heart C-nitrosoreductase.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Role of aniline metabolites in aniline-induced hemolytic anemia

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Synthesis and in vitro toxicity of hydroxylamine metabolites of sulfonamides.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Low concentrations of acid-soluble thiol (cysteine) in the blood plasma of HIV-1-infected patients.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Metabolic activation of eugenol by myeloperoxidase and polymorphonuclear leukocytes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Formation of 20-oxoleukotriene B4 by an alcohol dehydrogenase isolated from human neutrophils

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

25 May 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

25 May 2018

12 December 2020

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Direct and metabolism-dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

The role of leukocyte-generated reactive metabolites in the pathogenesis of idiosyncratic drug reactions

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Drug-induced toxic epidermal necrolysis (Lyell syndrome) in patients infected with the human immunodeficiency virus

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Polycyclic aromatic hydrocarbon (PAH) ortho-quinone conjugate chemistry: kinetics of thiol addition to PAH ortho-quinones and structures of thioether adducts of naphthalene-1,2-dione

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Glutathione deficiency and human immunodeficiency virus infection

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Contact sensitivity in the pig. II. Induction by intralymphatic infusion of DNP conjugated cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Abnormalities in the metabolism of acetaminophen in patients infected with the human immunodeficiency virus (HIV).

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Decreased release of glutathione into the systemic circulation of patients with HIV infection

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Neutrophils undergo apoptosis following ingestion of Escherichia coli.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Altered patterns of drug metabolism in patients with acquired immunodeficiency syndrome

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

The use of a three compartment in vitro model to investigate the role of hepatic drug metabolism in drug-induced blood dyscrasias

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Toxicity of sulfonamide-reactive metabolites in HIV-infected, HTLV-infected, and noninfected cells.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Trifluoroacetylation potentiates the humoral immune response to halothane in the guinea pig.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

The relationship between the disposition and immunogenicity of sulfamethoxazole in the rat

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Intracellular glutathione in the peripheral blood cells of HIV-infected patients: failure to show a deficiency

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective

3 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1565922

N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes

1 December 2018

1 reference

12 December 2020

Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers

1 reference

12 December 2020

Covalent binding of sulfamethoxazole reactive metabolites to human and rat liver subcellular fractions assessed by immunochemical detection

1 reference

12 December 2020

Surface thiols of human lymphocytes and their changes after in vitro and in vivo activation

1 reference

12 December 2020

Mechanisms involved in sodium arsenite-induced apoptosis of human neutrophils

1 reference

12 December 2020

Studies on the Enzymatic reduction of C-nitroso compounds. II. Multiple forms of liver C-nitrosoreductase and the identity with alcohol dehydrogenase

1 reference

12 December 2020

Necrosis and apoptosis: distinct modes of cell death with fundamentally different significance

1 reference

12 December 2020

Interaction of antimicrobial agents with human peripheral blood leucocytes: uptake and intracellular localization of certain sulphonamides and trimethoprims

1 reference

12 December 2020

Differences in metabolism of sulfonamides predisposing to idiosyncratic toxicity

1 reference

12 December 2020

Methodologies for the application of monobromobimane to the simultaneous analysis of soluble and protein thiol components of biological systems

1 reference

12 December 2020

Diagnosis of sulfonamide hypersensitivity reactions by in-vitro "rechallenge" with hydroxylamine metabolites

1 reference

12 December 2020

Peroxidase-dependent oxidation of sulfonamides by monocytes and neutrophils from humans and dogs

1 reference

12 December 2020

Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Implications for idiosyncratic toxicity

1 reference

12 December 2020

Reactions of nitrosonitrobenzenes with biological thiols: identification and reactivity of glutathion-S-yl conjugates

1 reference

12 December 2020

Time-course of toxicity of reactive sulfonamide metabolites

1 reference

12 December 2020

Pathogenesis of hypersensitivity reactions to drugs in patients with HIV infection: allergic or toxic?

1 reference

12 December 2020

Synthesis and reactions of nitroso sulphamethoxazole with biological nucleophiles: Implications for immune mediated toxicity

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJP.0702453

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.BJP.0702453

1 reference

15 November 2017

1 reference

15 November 2017

1 reference