(Q43200840)

English

Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity

scientific article published in February 2010

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scholarly article

1 reference

Europe PubMed Central

16 November 2017

Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activity (English)

1 reference

Europe PubMed Central

16 November 2017

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Europe PubMed Central

16 November 2017

Nico van Rooijen

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object named as

Nico van Rooijen

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Europe PubMed Central

16 November 2017

author name string

Rinke Stienstra

1

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Europe PubMed Central

16 November 2017

Fredy Saudale

2

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Europe PubMed Central

16 November 2017

Caroline Duval

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Europe PubMed Central

16 November 2017

Shohreh Keshtkar

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Europe PubMed Central

16 November 2017

Johanna E M Groener

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Europe PubMed Central

16 November 2017

Michael Müller

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Europe PubMed Central

16 November 2017

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publication date

1 February 2010

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Europe PubMed Central

16 November 2017

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Europe PubMed Central

16 November 2017

51

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Europe PubMed Central

16 November 2017

511-522

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Europe PubMed Central

16 November 2017

2

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Europe PubMed Central

16 November 2017

Role of Kupffer cells in host defense and liver disease

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Role of Kupffer cells in the pathogenesis of liver disease

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Non-alcoholic fatty liver disease is associated with cardiovascular disease risk markers

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Non-alcoholic steatohepatitis

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Steatohepatitis: a tale of two "hits"?

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Mechanisms of disease progression in nonalcoholic fatty liver disease

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Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates

1 reference

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Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor

1 reference

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Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes

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A PCR primer bank for quantitative gene expression analysis

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Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics.

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Bioconductor: open software development for computational biology and bioinformatics

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HPLC for simultaneous quantification of total ceramide, glucosylceramide, and ceramide trihexoside concentrations in plasma

1 reference

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Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate

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Hepatic steatosis in leptin-deficient mice is promoted by the PPARgamma target gene Fsp27.

1 reference

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Cidea is associated with lipid droplets and insulin sensitivity in humans

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A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

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7 January 2021

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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

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7 January 2021

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Nonalcoholic steatosis and steatohepatitis IV. Nonalcoholic fatty liver disease abnormalities in macrophage function and cytokines

1 reference

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Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.

1 reference

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Kupffer cell products and interleukin 1beta directly promote VLDL secretion and apoB mRNA up-regulation in rodent hepatocytes.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.23337

7 January 2021

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Interleukin 6 alleviates hepatic steatosis and ischemia/reperfusion injury in mice with fatty liver disease

1 reference

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Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis

1 reference

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7 January 2021

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Critical role of Kupffer cells in the management of diet-induced diabetes and obesity.

1 reference

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7 January 2021

based on heuristic

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Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

1 reference

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7 January 2021

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Peroxisome Proliferator-Activated Receptor α Protects against Obesity-Induced Hepatic Inflammation

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7 January 2021

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A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels

1 reference

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Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis

1 reference

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A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders

1 reference

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7 January 2021

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Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice

1 reference

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7 January 2021

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Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice

1 reference

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based on heuristic

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Peroxisome proliferator activated receptors and lipoprotein metabolism

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Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet

1 reference

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Comprehensive analysis of PPARalpha-dependent regulation of hepatic lipid metabolism by expression profiling

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A pilot trial of fenofibrate for the treatment of non-alcoholic fatty liver disease

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The acute phase response is associated with retinoid X receptor repression in rodent liver

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Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells

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Regulation of CYP4A1 and peroxisome proliferator-activated receptor alpha expression by interleukin-1beta, interleukin-6, and dexamethasone in cultured fetal rat hepatocytes

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Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice

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Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice.

1 reference

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Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome

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Inhibiting glycosphingolipid synthesis ameliorates hepatic steatosis in obese mice.

1 reference

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Negative transcriptional regulation of human colonic smooth muscle Cav1.2 channels by p50 and p65 subunits of nuclear factor-kappaB.

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NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity.

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Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

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Inhibition of JNK activation through NF-kappaB target genes

1 reference

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Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

1 reference

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Peroxisome proliferator-activated receptors in inflammation control

1 reference

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Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.

1 reference

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7 January 2021

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Identifiers

10.1002/HEP.23337

1 reference

Europe PubMed Central

16 November 2017

1 reference

Europe PubMed Central

16 November 2017

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