(Q43202230)

16 November 2017

Thioester derivatives of the natural product psammaplin A as potent histone deacetylase inhibitors (English)

1 reference

16 November 2017

1 reference

7

1 reference

16 November 2017

Franz-Josef Meyer-Almes

object named as

Franz-Josef Meyer-Almes

6

0 references

author name string

Matthias G J Baud

1

1 reference

16 November 2017

Thomas Leiser

2

1 reference

16 November 2017

Vanessa Petrucci

3

1 reference

16 November 2017

Mekala Gunaratnam

4

1 reference

16 November 2017

Stephen Neidle

5

1 reference

16 November 2017

15 January 2013

1 reference

Beilstein Journal of Organic Chemistry

16 November 2017

1 reference

16 November 2017

9

1 reference

16 November 2017

81-88

1 reference

Current limitations and future opportunities for epigenetic therapies.

16 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

On the function of the internal cavity of histone deacetylase protein 8: R37 is a crucial residue for catalysis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Epigenetic profiling of the antitumor natural product psammaplin A and its analogues

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

New synthetic strategies towards psammaplin A, access to natural product analogues for biological evaluation

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Characterisation of the in vitro activity of the depsipeptide histone deacetylase inhibitor spiruchostatin A.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Histone deacetylase inhibitors: molecular mechanisms of action

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Chromatin modifications and their function

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

The epigenomics of cancer

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Epigenetic therapy of cancer: past, present and future

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

The epigenetic progenitor origin of human cancer

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Epigenetics--an epicenter of gene regulation: histones and histone-modifying enzymes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

A new amidohydrolase from Bordetella or Alcaligenes strain FB188 with similarities to histone deacetylases

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

The language of covalent histone modifications

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Final results from a multicenter, international, pivotal study of romidepsin in refractory cutaneous T-cell lymphoma

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Psammaplin A is a natural prodrug that inhibits class I histone deacetylase.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Identification of a potent non-hydroxamate histone deacetylase inhibitor by mechanism-based drug design

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Psammaplins from the Sponge Pseudoceratina purpurea: Inhibition of Both Histone Deacetylase and DNA Methyltransferase

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Histone Deacetylase Inhibitors

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566764

Death Receptor Pathway Activation and Increase of ROS Production by the Triple Epigenetic Inhibitor UVI5008

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23400330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3762/BJOC.9.11

1 reference

16 November 2017

1 reference

16 November 2017

PubMed publication ID

23400330

1 reference