(Q43205446)

English

The specificity of cross‐reactivity: Promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness

scientific article published on October 1, 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

16 November 2017

The specificity of cross-reactivity: promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness (English)

1 reference

Europe PubMed Central

16 November 2017

The specificity of cross‐reactivity: Promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness (English)

1 reference

10.1110/PS.03172703

https://api.crossref.org/works/10.1110/PS.03172703

12 March 2024

1 reference

ChEBI release 2020-05-28

1 reference

ChEBI release 2020-05-28

4-bromo-1-hydroxyanthraquinone-2-carboxylic acid

1 reference

ChEBI release 2020-05-28

N-(2,4-dinitrophenyl)serine

1 reference

ChEBI release 2020-05-28

1 reference

ChEBI release 2020-05-28

N-(2,4-dinitrophenyl)-L-serine

1 reference

ChEBI release 2020-05-28

6-(4-hydroxy-5-iodo-3-nitrobenzamido)hexanoic acid

1 reference

ChEBI release 2020-05-28

N-(2,4-dinitrophenyl)proline

1 reference

ChEBI release 2020-05-28

1 reference

ChEBI release 2020-05-28

acenaphthenequinone

1 reference

ChEBI release 2020-05-28

3,4-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid

1 reference

ChEBI release 2020-05-28

N(6)-(2,4-dinitrophenyl)lysine

1 reference

ChEBI release 2020-05-28

N(6)-(2,4-dinitrophenyl)-L-lysine

1 reference

ChEBI release 2020-05-28

alizarin complexone

1 reference

ChEBI release 2020-05-28

1 reference

ChEBI release 2020-05-28

2,6-dihydroxyanthraquinone

1 reference

ChEBI release 2020-05-28

6-(4-hydroxy-3-nitrobenzamido)hexanoic acid

1 reference

ChEBI release 2020-05-28

1 reference

ChEBI release 2020-05-28

N-(2,4-dinitrophenyl)-L-proline

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Hydrophobic and Hydrophilic Interactions

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500876

12 March 2024

1 reference

10.1110/PS.03172703

https://api.crossref.org/works/10.1110/PS.03172703

12 March 2024

author name string

Leo C. James

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500876

12 March 2024

Dan S. Tawfik

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500876

12 March 2024

language of work or name

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14500876

12 March 2024

publication date

1 October 2003

1 reference

Europe PubMed Central

16 November 2017

full work available at URL

https://europepmc.org/articles/pmc2366915?pdf=render

Portable Document Format

online access status

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500876

12 March 2024

https://europepmc.org/articles/PMC2366915

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500876

12 March 2024

https://europepmc.org/articles/PMC2366915?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500876

12 March 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1110%2Fps.03172703

1 reference

10.1110/PS.03172703

https://api.crossref.org/works/10.1110/PS.03172703

12 March 2024

https://onlinelibrary.wiley.com/doi/pdf/10.1110/ps.03172703

1 reference

10.1110/PS.03172703

https://api.crossref.org/works/10.1110/PS.03172703

12 March 2024

Protein Science

1 reference

Europe PubMed Central

16 November 2017

12

1 reference

Europe PubMed Central

16 November 2017

10

1 reference

Europe PubMed Central

16 November 2017

2183-2193

1 reference

Europe PubMed Central

16 November 2017

Enzymes with extra talents: moonlighting functions and catalytic promiscuity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Antibody multispecificity mediated by conformational diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Immunology. Isomeric antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Catalytic and binding poly-reactivities shared by two unrelated proteins: The potential role of promiscuity in enzyme evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Antigenic mimicry, clonal selection and autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Mycoplasma-pneumoniae-induced thrombotic thrombocytopenic purpura

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Convergent solutions to binding at a protein-protein interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Catalytic promiscuity and the evolution of new enzymatic activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Moonlighting proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Conformational changes affect binding and catalysis by ester-hydrolysing antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Molecular mimicry and immune-mediated diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Wild isolates of murine cytomegalovirus induce myocarditis and antibodies that cross-react with virus and cardiac myosin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Molecular basis for the binding promiscuity of an anti-p24 (HIV-1) monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Immune versus natural selection: antibody aldolases with enzymic rates but broader scope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Antibody fragment Fv4155 bound to two closely related steroid hormones: the structural basis of fine specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Anatomy of the antibody molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Structural analysis of antibody specificity. Detailed comparison of five Fab'-steroid complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Mechanism of chymotrypsin. Structure, reactivity, and nonproductive binding relationships.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Mouse immunoglobulin allotypes: multiple differences between the nucleic acid sequences of the IgEa and IgEb alleles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Idiotypic selection of an antibody mutant with changed hapten binding specificity, resulting from a point mutation in position 50 of the heavy chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Generation of a catalytic antibody by site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Basic local alignment search tool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Mechanism of allergic cross-reactions—I. Multispecific binding of ligands to a mouse monoclonal anti-DNP IgE antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

The enzyme-linked immunosorbent assay (ELISA) (theory, technique and applications)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-non-self discrimination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Evidence for multispecificity of antibody molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2366915

25 May 2018

Conformational diversity and protein evolution--a 60-year-old hypothesis revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/14500876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of hybridomas secreting murine reaginic antibodies of anti-DNP specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14500876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The basics of binding: mechanisms of antigen recognition and mimicry by antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/14500876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of conserved amino acid residues in the complementarity determining regions on hapten-antibody interaction of anti-(4-hydroxy-3-nitrophenyl) acetyl antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/14500876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tyrosyl-tRNA synthetase recognizes a conserved tRNA-like structural motif in the group I intron catalytic core

1 reference

https://pubmed.ncbi.nlm.nih.gov/14500876

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1110/PS.03172703

1 reference

Europe PubMed Central

16 November 2017

1 reference

Europe PubMed Central

16 November 2017

1 reference

Europe PubMed Central

16 November 2017

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