(Q43214685)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

main subject

endoplasmic reticulum

0 references

author

Wei-Chieh Chiang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

8

Krzysztof Palczewski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

3

Sanae Sakami

1 reference

20 February 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

Heike Kroeger

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Carissa Messah

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Douglas Yasumura

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Michael T Matthes

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Judith A Coppinger

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Matthew M LaVail

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Jonathan H Lin

10

1 reference

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20 February 2020

publication date

2 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

published in

Molecular Neurobiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

52

1 reference

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20 February 2020

issue

1

1 reference

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20 February 2020

page(s)

679-695

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s12035-014-8881-8

20 February 2020

exact match

0 references

cites work

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Interaction of Nck1 and PERK phosphorylated at Y⁵⁶¹ negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content

25 May 2018

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Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects

25 May 2018

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P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis

25 May 2018

1 reference

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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

25 May 2018

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Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments

25 May 2018

1 reference

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Induction of endoplasmic reticulum stress genes, BiP and chop, in genetic and environmental models of retinal degeneration

25 May 2018

1 reference

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Mechanisms of age-related macular degeneration

25 May 2018

1 reference

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ER stress is involved in T17M rhodopsin-induced retinal degeneration.

25 May 2018

1 reference

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Derlin-1 deficiency is embryonic lethal, Derlin-3 deficiency appears normal, and Herp deficiency is intolerant to glucose load and ischemia in mice

25 May 2018

1 reference

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IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsin

25 May 2018

1 reference

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Defining human ERAD networks through an integrative mapping strategy

25 May 2018

1 reference

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Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

25 May 2018

1 reference

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The unfolded protein response: from stress pathway to homeostatic regulation

25 May 2018

1 reference

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Chemistry and biology of vision

25 May 2018

1 reference

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Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response

25 May 2018

1 reference

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Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Probing mechanisms of photoreceptor degeneration in a new mouse model of the common form of autosomal dominant retinitis pigmentosa due to P23H opsin mutations

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

The cell biology of vision

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Fine-tuning of the unfolded protein response: Assembling the IRE1alpha interactome

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Inhibition of p97-dependent protein degradation by Eeyarestatin I

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

IRE1 signaling affects cell fate during the unfolded protein response

25 May 2018

1 reference

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XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Involvement of ER stress in retinal cell death

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response

25 May 2018

1 reference

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GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development

25 May 2018

1 reference

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G protein-coupled receptor rhodopsin

25 May 2018

1 reference

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XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

25 May 2018

1 reference

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Rhodopsin signaling and organization in heterozygote rhodopsin knockout mice

25 May 2018

1 reference

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MS1, MS2, and SQT-three unified, compact, and easily parsed file formats for the storage of shotgun proteomic spectra and identifications.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin

25 May 2018

1 reference

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XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

25 May 2018

1 reference

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Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Phototransduction in transgenic mice after targeted deletion of the rod transducin alpha -subunit

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Endoplasmic reticulum (ER)-associated degradation of misfolded N-linked glycoproteins is suppressed upon inhibition of ER mannosidase I.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Molecular genetics of human retinal disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Morphological, physiological, and biochemical changes in rhodopsin knockout mice

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Ectopic photoreceptor cells and cell death in the developing rat retina

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

The electroretinogram of the isolated rat retina

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Kinetics of rod outer segment renewal in the developing mouse retina

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

A comparative study of methods of photoreceptor morphometry.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Basic fibroblast growth factor and local injury protect photoreceptors from light damage in the rat

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Transgenic mice with a rhodopsin mutation (Pro23His): a mouse model of autosomal dominant retinitis pigmentosa

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Genetic regulation of light damage to photoreceptors.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Endoplasmic reticulum stress is activated in light-induced retinal degeneration

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Cross-correlation algorithm for calculation of peptide molecular weight from tandem mass spectra

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

A transgenic mouse model for monitoring endoplasmic reticulum stress

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Evidence for two apoptotic pathways in light-induced retinal degeneration

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4383737

Comparative light and electron microscopic study of retinal histogenesis in normal and rd mutant mice

15 August 2018

1 reference

12 December 2020

C57BL/6J Mice With inherited Retinal Degeneration

1 reference

12 December 2020

Influence of eye pigmentation and light deprivation on inherited retinal dystrophy in the rat

1 reference

12 December 2020

A null mutation in the rhodopsin gene causes rod photoreceptor dysfunction and autosomal recessive retinitis pigmentosa

1 reference

12 December 2020

Retinopathy induced in mice by targeted disruption of the rhodopsin gene

1 reference

12 December 2020

The postnatal development of the retina in the normal and rodless CBA mouse: a light and electron microscopic study

1 reference

12 December 2020

10.1007/S12035-014-8881-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

25270370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25270370%20AND%20SRC:MED&resulttype=core&format=json