(Q43215257)

16 November 2017

From breaking bad to worse: exploiting homologous DNA repair deficiency in cancer (English)

1 reference

16 November 2017

Michael T Hemann

1

1 reference

16 November 2017

1 May 2014

1 reference

16 November 2017

1 reference

16 November 2017

4

1 reference

16 November 2017

5

1 reference

16 November 2017

516-518

1 reference

A functional cancer genomics screen identifies a druggable synthetic lethal interaction between MSH3 and PRKDC.

16 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

Therapeutic targeting of a robust non-oncogene addiction to PRKDC in ATM-defective tumors

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

Comprehensive molecular characterization of human colon and rectal cancer

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

Exploiting synthetic lethal interactions for targeted cancer therapy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

The combined status of ATM and p53 link tumor development with therapeutic response

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

RNA silencing of checkpoint regulators sensitizes p53-defective prostate cancer cells to chemotherapy while sparing normal cells

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4384127

10.1158/2159-8290.CD-14-0316

15 August 2018

Identifiers

DOI

1 reference

16 November 2017

1 reference

PMC publication ID

4384127

16 November 2017

PubMed publication ID

24795010

1 reference

PMC publication ID

4384127