(Q27852340)

1

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Mathias Daheim

2

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Grit S Herter-Sprie

3

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Johannes Winkler

4

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Christian Fritz

5

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Roman K Thomas

7

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Karl-Anton Kreuzer

8

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Lukas P Frenzel

9

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Parisa Monfared

10

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Jorge Martins-Boucas

11

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Shuhua Chen

12

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Hans Christian Reinhardt

Science Translational Medicine

13

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language of work or name

English

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publication date

12 June 2013

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published in

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volume

5

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page(s)

189ra78

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issue

189

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cites work

The many substrates and functions of ATM

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

Somatic mutations affect key pathways in lung adenocarcinoma

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

Genomic aberrations and survival in chronic lymphocytic leukemia

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

The combined status of ATM and p53 link tumor development with therapeutic response

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

Rapid activation of ATR by ionizing radiation requires ATM and Mre11

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

Human CtIP promotes DNA end resection

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3005814

ATR: an essential regulator of genome integrity

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Mechanism of eukaryotic homologous recombination

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Playing the end game: DNA double-strand break repair pathway choice

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

The DNA damage response: ten years after

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

ATM gene deletion in patients with adult acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Genetic abnormalities and clinical outcome in chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Biallelic ATM inactivation significantly reduces survival in patients treated on the United Kingdom Leukemia Research Fund Chronic Lymphocytic Leukemia 4 trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Mechanisms of double-strand break repair in somatic mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Repair of DNA double strand breaks by non-homologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

The controlling role of ATM in homologous recombinational repair of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Ionizing radiation-induced Rad51 nuclear focus formation is cell cycle-regulated and defective in both ATM(-/-) and c-Abl(-/-) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Sister chromatid exchanges occur in G2-irradiated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

The role of homologous recombination in radiation-induced double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Radiosensitive melanoma cell line with mutation of the gene for ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

At loose ends: resecting a double-strand break

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

DNA end resection: many nucleases make light work

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

SF3B1 and other novel cancer genes in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

The DNA damage response and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

The ATM/p53 pathway is commonly targeted for inactivation in squamous cell carcinoma of the head and neck (SCCHN) by multiple molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

Mantle cell lymphoma is characterized by inactivation of the ATM gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005814

10.1126/SCITRANSLMED.3005814

21 January 2018

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3269306

OpenCitations bibliographic resource ID

3269306

1 reference