(Q43217966)

English

Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta

scientific article published on 6 November 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta (English)

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

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1 reference

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inferred from title

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object named as

Marc Freichel

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

8

object named as

Veit Flockerzi

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

author name string

Angela M Bair

1

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Europe PubMed Central

PMC publication ID

16 November 2017

Prabhakar B Thippegowda

2

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Europe PubMed Central

PMC publication ID

16 November 2017

Ni Cheng

4

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Europe PubMed Central

PMC publication ID

16 November 2017

Richard D Ye

5

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

Stephen M Vogel

6

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

Yanni Yu

7

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

Asrar B Malik

9

1 reference

Europe PubMed Central

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16 November 2017

Chinnaswamy Tiruppathi

10

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Europe PubMed Central

PMC publication ID

16 November 2017

language of work or name

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publication date

6 November 2008

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Europe PubMed Central

PMC publication ID

16 November 2017

number of pages

12

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Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

16 November 2017

284

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16 November 2017

1

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Europe PubMed Central

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16 November 2017

563-574

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels

1 reference

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1 reference

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25 May 2018

Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components

1 reference

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Ca2+ signaling, TRP channels, and endothelial permeability

1 reference

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25 May 2018

Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta

1 reference

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Ca2+/calmodulin-dependent protein kinase II is a modulator of CARMA1-mediated NF-kappaB activation

1 reference

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Proteinase-activated receptors (PARs): crossroads between innate immunity and coagulation

1 reference

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25 May 2018

Ca2+ influx induced by protease-activated receptor-1 activates a feed-forward mechanism of TRPC1 expression via nuclear factor-kappaB activation in endothelial cells

1 reference

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Metformin inhibits cytokine-induced nuclear factor kappaB activation via AMP-activated protein kinase activation in vascular endothelial cells

1 reference

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The interactions between inflammation and coagulation

1 reference

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Thrombin induces expression of FGF-2 via activation of PI3K-Akt-Fra-1 signaling axis leading to DNA synthesis and motility in vascular smooth muscle cells

1 reference

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25 May 2018

Store-operated calcium channels

1 reference

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RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65.

1 reference

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25 May 2018

Signaling to NF-kappaB

1 reference

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25 May 2018

Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes

1 reference

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25 May 2018

Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status.

1 reference

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25 May 2018

Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm

1 reference

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Subunit composition of mammalian transient receptor potential channels in living cells

1 reference

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25 May 2018

Missing pieces in the NF-kappaB puzzle

1 reference

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25 May 2018

Transcriptional mechanisms of acute lung injury

1 reference

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25 May 2018

Thrombin stimulation of the vascular cell adhesion molecule-1 promoter in endothelial cells is mediated by tandem nuclear factor-kappa B and GATA motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610508

25 May 2018

Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610508

25 May 2018

Ca2+/calmodulin-dependent protein kinase IV stimulates nuclear factor-kappa B transactivation via phosphorylation of the p65 subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610508

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Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610508

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Ca2+-dependent cell signaling through calmodulin-activated protein phosphatase and protein kinases minireview series

1 reference

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Defining Ca2+/calmodulin-dependent protein kinase cascades in transcriptional regulation

1 reference

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Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

1 reference

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p38 MAPK and NF-kappa B collaborate to induce interleukin-6 gene expression and release. Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system

1 reference

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25 May 2018

Store-operated cation channels in the heart and cells of the cardiovascular system

1 reference

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Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

1 reference

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Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion.

1 reference

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

1 reference

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Calcium oscillations increase the efficiency and specificity of gene expression

1 reference

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p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

1 reference

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Differential activation of transcription factors induced by Ca2+ response amplitude and duration

1 reference

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Mechanism of endothelial nitric oxide synthase phosphorylation and activation by thrombin.

1 reference

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1 reference

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Activating AMP-activated protein kinase without AMP.

1 reference

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AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells.

1 reference

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Tumor necrosis factor-alpha induces nuclear factor-kappaB-dependent TRPC1 expression in endothelial cells

1 reference

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Activation of protein kinase C delta by IFN-gamma

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15 August 2018

TRPC1 is required for functional store-operated Ca2+ channels. Role of acidic amino acid residues in the S5-S6 region.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2610508

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1 reference

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Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C delta mediates the activation.

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Synergistic effects of tumor necrosis factor-alpha and thrombin in increasing endothelial permeability

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Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function

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Store-operated calcium entry and increased endothelial cell permeability.

1 reference

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Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galpha(q) and Gbetagamma regulate PAR-1 signaling of thrombin-induced NF-kappaB activation and ICAM-1 transcription in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abrogation of thrombin-induced increase in pulmonary microvascular permeability in PAR-1 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18990707

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M803984200

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

16 November 2017

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