(Q43221614)

16 November 2017

Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo (English)

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Florence Debacq-Chainiaux

16 November 2017

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series ordinal

1

object named as

Florence Debacq-Chainiaux

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16 November 2017

4

Olivier Toussaint

1 reference

16 November 2017

Jorge D Erusalimsky

2

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PubMed ID

20010931

16 November 2017

Judith Campisi

series ordinal

3

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16 November 2017

1 January 2009

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16 November 2017

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16 November 2017

4

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16 November 2017

1798-1806

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16 November 2017

12

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https://scigraph.springernature.com/pub.10.1038/nprot.2009.191

16 November 2017

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cites work

Hayflick, his limit, and cellular ageing.

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Cellular senescence: when bad things happen to good cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Role of TGF-β1-independent changes in protein neosynthesis, p38αMAPK, and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Cellular senescence in cancer and aging

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

The role of chondrocyte senescence in osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Cellular senescence in vivo: its relevance in ageing and cardiovascular disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Cellular senescence in the pathogenesis of benign prostatic hyperplasia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Cytochemical detection of a senescence-associated beta-galactosidase in endothelial and smooth muscle cells from human and rabbit blood vessels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Residual bodies and "aging" in cultured human glia cells. Effect of entrance into phase 3 and prolonged periods of confluence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Replicative senescence: a critical review.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Morphologic changes accompanying senescence of cultured human diploid cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Senescence-associated beta-galactosidase is lysosomal beta-galactosidase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

A beta-galactosidase gene mutation identified in both Morquio B disease and infantile GM1 gangliosidosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Subcytotoxic H2O2 stress triggers a release of transforming growth factor-beta 1, which induces biomarkers of cellular senescence of human diploid fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16(INK-4A).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

UVB-induced senescence in human keratinocytes requires a functional insulin-like growth factor-1 receptor and p53.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Changing medium and passaging cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress-induced premature senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Stress-induced premature senescence or stress-induced senescence-like phenotype: one in vivo reality, two possible definitions?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Oxidative stress shortens telomeres

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

ssDNA fragments induce cell senescence by telomere uncapping

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Mapping mechanisms and charting the time course of premature cell senescence and apoptosis: lysosomal dysfunction and ganglioside accumulation in endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.191

Human beta-galactosidase gene mutations in GM1-gangliosidosis: a common mutation among Japanese adult/chronic cases

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20010931

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20010931

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20010931

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NPROT.2009.191

1 reference

PubMed ID

20010931

Dimensions Publication ID

16 November 2017

0 references

1 reference

PubMed ID

20010931