(Q43235606)

16 November 2017

title

Brostallicin (PNU-166196), a new minor groove DNA binder: preclinical and clinical activity (English)

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16 November 2017

1

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16 November 2017

7

Giovanni Scambia

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16 November 2017

Sara Mainenti

2

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16 November 2017

Antonella Pietragalla

3

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16 November 2017

Gabriella Ferrandina

4

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16 November 2017

Gilda Foco

5

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16 November 2017

Valeria Masciullo

6

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16 November 2017

language of work or name

English

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publication date

1 December 2009

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Expert Opinion on Investigational Drugs

16 November 2017

published in

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16 November 2017

volume

18

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16 November 2017

issue

12

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16 November 2017

page(s)

1939-1946

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DNA minor groove binding ligands: a new class of anticancer agents

16 November 2017

cites work

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https://api.crossref.org/works/10.1517%2F13543780903401284

Brostallicin: a new concept in minor groove DNA binder development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Alpha-bromoacryloyl derivative of distamycin A (PNU 151807): a new non-covalent minor groove DNA binder with antineoplastic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Cytotoxic alpha-bromoacrylic derivatives of low molecular weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

The role of glutathione-S-transferase polymorphisms in ovarian cancer survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Intracellular glutathione heterogeneity in L1210 murine leukemia sublines made resistant to DNA-interacting anti-neoplastic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

A new class of cytotoxic DNA minor groove binders: alpha-halogenoacrylic derivatives of pyrrolecarbamoyl oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Cytotoxic alpha-halogenoacrylic derivatives of distamycin A and congeners

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

GSTP1 CpG island hypermethylation as a molecular biomarker for prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Mechanisms of in situ activation for DNA-targeting antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Induction of glutathione-dependent DNA double-strand breaks by the novel anticancer drug brostallicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Estimation of the haematological toxicity of minor groove alkylators using tests on human cord blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

A phase I dose-escalation and pharmacokinetic study of brostallicin (PNU-166196A), a novel DNA minor groove binder, in adult patients with advanced solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Phase I and pharmacokinetic study of lapatinib and docetaxel in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Brostallicin, an agent with potential activity in metastatic soft tissue sarcoma: a phase II study from the European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Doxorubicin-induced DNA intercalation and scavenging by nuclear glutathione S-transferase pi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Blood glutathione as a surrogate marker of cancer tissue glutathione S-transferase activity in non-small cell lung cancer and squamous cell carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543780903401284

10.1517/13543780903401284

21 January 2018

Identifiers

DOI

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16 November 2017

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