(Q43254285)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19859789%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Use of pifithrin to inhibit p53-mediated signalling of TNF in dystrophic muscles of mdx mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19859789%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

0 references

4

1 reference

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11 February 2020

Miranda Grounds

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19859789%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Felicity J Waters

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19859789%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Thea Shavlakadze

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19859789%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Matthew J McIldowie

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19859789%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

publication date

27 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19859789%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biochemistry

11 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19859789%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

337

1 reference

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11 February 2020

issue

1-2

1 reference

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11 February 2020

page(s)

119-131

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19859789%20AND%20SRC:MED&resulttype=core&format=json

Inflammatory processes in muscle injury and repair

11 February 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-009-0291-2

A multidisciplinary evaluation of the effectiveness of cyclosporine a in dystrophic mdx mice.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11010-009-0291-2

Insulin-like growth factors (IGF-I and IGF-II) inhibit C2 skeletal myoblast differentiation and enhance TNF alpha-induced apoptosis

21 January 2018

1 reference

12 December 2020

Reduced muscle necrosis and long-term benefits in dystrophic mdx mice after cV1q (blockade of TNF) treatment

1 reference

12 December 2020

Cromolyn administration (to block mast cell degranulation) reduces necrosis of dystrophic muscle in mdx mice

1 reference

12 December 2020

Inhibitors of apoptosis in lymphocytes: synthesis and biological evaluation of compounds related to pifithrin-alpha.

1 reference

12 December 2020

Pifithrin-alpha, an inhibitor of p53 transactivation, alters the inflammatory process and delays tendon healing following acute injury

1 reference

12 December 2020

The muscular dystrophies

1 reference

12 December 2020

A sensitive assay of tumor necrosis factor alpha in sera from Duchenne muscular dystrophy patients

1 reference

12 December 2020

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

1 reference

12 December 2020

Nuclear factor kappa-B blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice

1 reference

12 December 2020

Voluntary exercise decreases progression of muscular dystrophy in diaphragm of mdx mice

1 reference

12 December 2020

Implications of cross-talk between tumour necrosis factor and insulin-like growth factor-1 signalling in skeletal muscle.

1 reference

12 December 2020

Myogenic programs of mouse muscle cell lines: expression of myosin heavy chain isoforms, MyoD1, and myogenin

1 reference

12 December 2020

Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism

1 reference

12 December 2020

Prospective therapeutic applications of p53 inhibitors

1 reference

12 December 2020

Administration of the non-steroidal anti-inflammatory drug ibuprofen increases macrophage concentrations but reduces necrosis during modified muscle use

1 reference

12 December 2020

Effect of voluntary wheel-running exercise on muscles of the mdx mouse

1 reference

12 December 2020

Suppression of p53: a new approach to overcome side effects of antitumor therapy

1 reference

12 December 2020

p53 and NF-kappaB crosstalk: IKKalpha tips the balance

1 reference

12 December 2020

Post-translational modifications and activation of p53 by genotoxic stresses

1 reference

12 December 2020

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1 reference

12 December 2020

Muscle damage in mdx (dystrophic) mice: role of calcium and reactive oxygen species.

1 reference

12 December 2020

Inhibition of p53 response in tumor stroma improves efficacy of anticancer treatment by increasing antiangiogenic effects of chemotherapy and radiotherapy in mice

1 reference

12 December 2020

Long-term benefits of deflazacort treatment for boys with Duchenne muscular dystrophy in their second decade.

1 reference

12 December 2020

Interference with p53 protein inhibits hematopoietic and muscle differentiation

1 reference

12 December 2020

Protein-DNA array-based identification of transcription factor activities differentially regulated in skeletal muscle of normal and dystrophin-deficient mdx mice.

1 reference

12 December 2020

The effect of age and temperature on mdx muscle fatigue

1 reference

12 December 2020

A nitric oxide synthase transgene ameliorates muscular dystrophy in mdx mice

1 reference

12 December 2020

Inhibition of p53, p21 and Bax by pifithrin-alpha does not affect UV induced apoptotic response in CS-B cells

1 reference

12 December 2020

Paxillin: a focal adhesion-associated adaptor protein

1 reference

12 December 2020

The dystrophin-associated protein complex

1 reference

12 December 2020

Skeletal muscle diseases, inflammation, and NF-kappaB signaling: insights and opportunities for therapeutic intervention

1 reference

12 December 2020

A chronic inflammatory response dominates the skeletal muscle molecular signature in dystrophin-deficient mdx mice

1 reference

12 December 2020

IFN-gamma prevents TNF-alpha-induced apoptosis in C2C12 myotubes through down-regulation of TNF-R2 and increased NF-kappaB activity

1 reference

12 December 2020

Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation

1 reference

12 December 2020

Accumulation of an inactive form of p53 protein in cells treated with TNF alpha

1 reference

12 December 2020

The dystrophin glycoprotein complex: signaling strength and integrity for the sarcolemma

1 reference

12 December 2020

Role of tumour necrosis factor alpha, but not of cyclo-oxygenase-2-derived eicosanoids, on functional and morphological indices of dystrophic progression in mdx mice: a pharmacological approach.

1 reference

12 December 2020

The p53 inhibitor pifithrin-alpha forms a sparingly soluble derivative via intramolecular cyclization under physiological conditions

1 reference

12 December 2020

Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death

1 reference

12 December 2020

Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy

1 reference

12 December 2020

Reduced necrosis of dystrophic muscle by depletion of host neutrophils, or blocking TNFalpha function with Etanercept in mdx mice

1 reference

12 December 2020

Activated p53 induces NF-kappaB DNA binding but suppresses its transcriptional activation

1 reference

12 December 2020

Dystrophin: the protein product of the Duchenne muscular dystrophy locus

1 reference

12 December 2020

Tumor necrosis factor-alpha-induced apoptosis is associated with suppression of insulin-like growth factor binding protein-5 secretion in differentiating murine skeletal myoblasts

1 reference

12 December 2020

TNFalpha inhibits skeletal myogenesis through a PW1-dependent pathway by recruitment of caspase pathways.

1 reference

12 December 2020

Increased nuclear proteins in muscle satellite cells in aged animals as compared to young growing animals

1 reference

12 December 2020

Expression of tumor necrosis factor-alpha in regenerating muscle fibers in inflammatory and non-inflammatory myopathies.

1 reference

12 December 2020

How TNF was recognized as a key mechanism of disease

1 reference

12 December 2020

The signaling adaptors and pathways activated by TNF superfamily

1 reference

12 December 2020

Muscle cachexia is regulated by a p53-PW1/Peg3-dependent pathway.

1 reference

12 December 2020

Duchenne muscular dystrophy: focus on pharmaceutical and nutritional interventions.

1 reference

12 December 2020

p53 mediates particulate matter-induced alveolar epithelial cell mitochondria-regulated apoptosis

1 reference

12 December 2020

Integrating cell-signalling pathways with NF-kappaB and IKK function

1 reference

12 December 2020

Novel cyclized Pifithrin-alpha p53 inactivators: synthesis and biological studies

1 reference

12 December 2020

Do immune cells promote the pathology of dystrophin-deficient myopathies?

1 reference

12 December 2020

Report on the 124th ENMC International Workshop. Treatment of Duchenne muscular dystrophy; defining the gold standards of management in the use of corticosteroids. 2-4 April 2004, Naarden, The Netherlands

1 reference

12 December 2020

Dystrophin protects the sarcolemma from stresses developed during muscle contraction

1 reference

12 December 2020

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

1 reference

12 December 2020

Oxidative stress as a therapeutic target during muscle wasting: considering the complex interactions.

1 reference

12 December 2020

Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation

1 reference

12 December 2020

Anti-TNFalpha (Remicade) therapy protects dystrophic skeletal muscle from necrosis.

1 reference

12 December 2020

Respiratory and limb muscle weakness induced by tumor necrosis factor-alpha: involvement of muscle myofilaments

1 reference

12 December 2020

Persistent and improved functional gain in mdx dystrophic mice after treatment with L-arginine and deflazacort

1 reference

12 December 2020

X chromosome-linked muscular dystrophy (mdx) in the mouse

1 reference

12 December 2020

Therapeutics in duchenne muscular dystrophy

1 reference

12 December 2020