(Q43258139)

17 November 2017

title

SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7. (English)

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17 November 2017

7

Charles Duyckaerts

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17 November 2017

Alexandre Janer

1

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17 November 2017

Andreas Werner

2

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17 November 2017

Junko Takahashi-Fujigasaki

3

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17 November 2017

Aurélie Daret

4

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17 November 2017

Hiroto Fujigasaki

5

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17 November 2017

Koji Takada

6

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17 November 2017

Alexis Brice

8

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17 November 2017

Anne Dejean

9

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17 November 2017

Annie Sittler

10

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17 November 2017

publication date

1 January 2010

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17 November 2017

published in

Human Molecular Genetics

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17 November 2017

volume

19

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17 November 2017

issue

1

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17 November 2017

page(s)

181-195

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Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion

17 November 2017

cites work

1 reference

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Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes

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A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing

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Two populations of neuronal intranuclear inclusions in SCA7 differ in size and promyelocytic leukaemia protein content

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Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions

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PML nuclear bodies and neuronal intranuclear inclusion in polyglutamine diseases

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Post-translational modifications of expanded polyglutamine proteins: impact on neurotoxicity.

21 January 2018

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SUMO on the road to neurodegeneration

21 January 2018

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SUMO, a ubiquitin-like modifier implicated in neurodegeneration

21 January 2018

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Protein modification by SUMO

21 January 2018

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Nuclear and unclear functions of SUMO

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Concepts in sumoylation: a decade on

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SUMO junction-what's your function? New insights through SUMO-interacting motifs

21 January 2018

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Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1).

21 January 2018

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SUMOylation of the polyglutamine repeat protein, ataxin-1, is dependent on a functional nuclear localization signal

21 January 2018

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SUMO modification of Huntingtin and Huntington's disease pathology

21 January 2018

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Functional transplantation of the sumoylation machinery into Escherichia coli

21 January 2018

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PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins

21 January 2018

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A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

21 January 2018

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SUMOylation substrates in neuronal intranuclear inclusion disease

21 January 2018

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SCA7 knockin mice model human SCA7 and reveal gradual accumulation of mutant ataxin-7 in neurons and abnormalities in short-term plasticity.

21 January 2018

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Small ubiquitin-like modifier (SUMO) modification of the androgen receptor attenuates polyglutamine-mediated aggregation

21 January 2018

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SUMO-1 co-localized with mutant atrophin-1 with expanded polyglutamines accelerates intranuclear aggregation and cell death

21 January 2018

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Global analysis of protein sumoylation in Saccharomyces cerevisiae

21 January 2018

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Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25

21 January 2018

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Sumoylation of the yeast Gcn5 protein.

21 January 2018

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SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles

21 January 2018

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A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

21 January 2018

1 reference

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Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

21 January 2018

1 reference

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Regulation and function of SUMO modification

21 January 2018

1 reference

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Protein aggregation and neurodegenerative disease

21 January 2018

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Opinion: What is the role of protein aggregation in neurodegeneration?

21 January 2018

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Pathogenesis of polyglutamine disorders: aggregation revisited

21 January 2018

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Huntington's disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

21 January 2018

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Sumoylation and human disease pathogenesis

21 January 2018

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Enhanced SUMOylation in polyglutamine diseases

21 January 2018

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Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila

21 January 2018

1 reference

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Rhes, a striatal specific protein, mediates mutant-huntingtin cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

Role of heat shock proteins during polyglutamine neurodegeneration: mechanisms and hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

SUMO: regulating the regulator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

Oxidative stress in neurodegeneration and available means of protection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

Common properties of nuclear body protein SP100 and TIF1alpha chromatin factor: role of SUMO modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates

21 January 2018

1 reference

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Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

Distribution of ataxin-7 in normal human brain and retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

A Proteomic Strategy for Gaining Insights into Protein Sumoylation in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDP478

21 January 2018

Identifiers

DOI

10.1093/HMG/DDP478

1 reference

17 November 2017

1 reference