(Q43264545)

17 November 2017

YM-53601, a novel squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in several animal species (English)

1 reference

17 November 2017

1 reference

1 reference

T Ugawa

1

1 reference

17 November 2017

H Kakuta

2

1 reference

17 November 2017

H Moritani

3

1 reference

17 November 2017

K Matsuda

4

1 reference

17 November 2017

T Ishihara

5

1 reference

17 November 2017

M Yamaguchi

6

1 reference

17 November 2017

S Naganuma

7

1 reference

17 November 2017

Y Iizumi

8

1 reference

17 November 2017

H Shikama

9

1 reference

17 November 2017

language of work or name

English

0 references

publication date

1 September 2000

1 reference

British Journal of Pharmacology

17 November 2017

1 reference

17 November 2017

131

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17 November 2017

1

1 reference

17 November 2017

63-70

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Protein measurement with the Folin phenol reagent

17 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Mechanism of action of fibrates on lipid and lipoprotein metabolism

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

RPR 107393, a potent squalene synthase inhibitor and orally effective cholesterol-lowering agent: comparison with inhibitors of HMG-CoA reductase

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Discovery, biosynthesis, and mechanism of action of the zaragozic acids: potent inhibitors of squalene synthase

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Evidence of plasma CoQ10-lowering effect by HMG-CoA reductase inhibitors: a double-blind, placebo-controlled study

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Prevention of coronary heart disease in clinical practice. Recommendations of the Task Force of the European Society of Cardiology, European Atherosclerosis Society and European Society of Hypertension

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Pharmacology of competitive inhibitors of HMG-CoA reductase.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

CS-514, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase: tissue-selective inhibition of sterol synthesis and hypolipidemic effect on various animal species

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Structure and biochemical effects of fenofibrate

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Dietary saturated triacylglycerols suppress hepatic low density lipoprotein receptor activity in the hamster

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Lovastatin decreases coenzyme Q levels in humans

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Lovastatin decreases coenzyme Q levels in rats

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

NB-598: a potent competitive inhibitor of squalene epoxidase

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Effect of simvastatin on receptor mediated metabolism of low density lipoprotein in guinea pigs

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Bisphosphonates used for the treatment of bone disorders inhibit squalene synthase and cholesterol biosynthesis.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Efficacy and safety of a new hydroxymethylglutaryl-coenzyme A reductase inhibitor, atorvastatin, in patients with combined hyperlipidemia: comparison with fenofibrate.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572301

Apolipoprotein A-I of primates

15 August 2018

1 reference

12 December 2020

Plasma and hepatic apoE isoproteins of nonhuman primates. Differences in apoE among humans, apes, and New and Old World monkeys

1 reference

12 December 2020

The recognition and management of hyperlipidaemia in adults: A policy statement of the European Atherosclerosis Society

1 reference

12 December 2020

Hyperlipoproteinemia as a risk factor for ischemic heart disease

1 reference

12 December 2020

Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo

1 reference

12 December 2020

Effect of squalestatin 1 on the biosynthesis of the mevalonate pathway lipids

1 reference

12 December 2020

Inhibition of mammalian squalene synthetase activity by zaragozic acid A is a result of competitive inhibition followed by mechanism-based irreversible inactivation

1 reference

12 December 2020

Pancreatitis and rhabdomyolysis associated with lovastatin-gemfibrozil therapy

1 reference

12 December 2020

Inhibition of squalene synthase of rat liver by novel 3' substituted quinuclidines

1 reference

12 December 2020

RPR 101821, a new potent cholesterol-lowering agent: inhibition of squalene synthase and 7-dehydrocholesterol reductase

1 reference

12 December 2020

Squalene synthase inhibition alters metabolism of nonsterols in rat liver

1 reference

12 December 2020

The mechanism of the diurnal variation of hepatic HMG-CoA reductase activity in the rat

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0703545

1 reference

17 November 2017

1 reference

17 November 2017

PubMed publication ID

10960070

1 reference