(Q43264688)

English

Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock

scientific article published in June 2000

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scholarly article

1 reference

Europe PubMed Central

17 November 2017

Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock (English)

1 reference

Europe PubMed Central

17 November 2017

Helder Mota-Filipe

2

1 reference

Europe PubMed Central

17 November 2017

author name string

M C McDonald

1

1 reference

Europe PubMed Central

17 November 2017

J A Wright

3

1 reference

Europe PubMed Central

17 November 2017

M Abdelrahman

4

1 reference

Europe PubMed Central

17 November 2017

M D Threadgill

5

1 reference

Europe PubMed Central

17 November 2017

A S Thompson

6

1 reference

Europe PubMed Central

17 November 2017

C Thiemermann

7

1 reference

Europe PubMed Central

17 November 2017

language of work or name

0 references

publication date

1 June 2000

1 reference

Europe PubMed Central

17 November 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

17 November 2017

130

1 reference

Europe PubMed Central

17 November 2017

4

1 reference

Europe PubMed Central

17 November 2017

843-850

1 reference

Europe PubMed Central

17 November 2017

Inhibitors of poly (ADP-ribose) synthetase protect rat cardiomyocytes against oxidant stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Synthesis of 3-substituted benzamides and 5-substituted isoquinolin-1(2H)-ones and preliminary evaluation as inhibitors of poly(ADP-ribose)polymerase (PARP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

ADP-ribosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Mechanisms of oxidant-mediated cell injury. The glycolytic and mitochondrial pathways of ADP phosphorylation are major intracellular targets inactivated by hydrogen peroxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Poly(ADP-ribose) in the cellular response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Direct measurement of free radical generation following reperfusion of ischemic myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Oxygen-derived free radicals in postischemic tissue injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Dihydroisoquinolinones: the design and synthesis of a new series of potent inhibitors of poly(ADP-ribose) polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

25 May 2018

Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

15 August 2018

3-Aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, improves hemodynamics and prolongs survival in a porcine model of hemorrhagic shock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

15 August 2018

Inhibitors of the activity of poly (ADP-ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

15 August 2018

Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

15 August 2018

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572143

15 August 2018

A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation and Claisen condensation products of 3-nitro-o-xylene

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical demonstration of poly(adenosine diphosphate-ribose) synthetase in bovine tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA strand breaks, NAD metabolism, and programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen injury to cultured pulmonary artery endothelial cells: mediation by poly(ADP-ribose) polymerase activation causing NAD depletion and altered energy balance

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemiluminescent measurement of increased free radical formation after ischemia/reperfusion. Mechanisms of free radical formation in the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: reductively triggered release of the PARP inhibitor 5-bromoisoquinolinone

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arsenicals in the isoquinoline series

1 reference

https://pubmed.ncbi.nlm.nih.gov/10864891

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0703391

1 reference

Europe PubMed Central

17 November 2017

1 reference

Europe PubMed Central

17 November 2017

1 reference

Europe PubMed Central

17 November 2017

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0 references

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