(Q43269848)

17 November 2017

title

Inhibition of extracellular signal-regulated kinase 1 by adenovirus mediated small interfering RNA attenuates hepatic fibrosis in rats (English)

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17 November 2017

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Wei Zhong

1

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17 November 2017

Wei-Feng Shen

2

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17 November 2017

Bei-Fang Ning

3

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17 November 2017

Ping-Fang Hu

4

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17 November 2017

Yong Lin

5

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17 November 2017

Hai-Yan Yue

6

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17 November 2017

Chuan Yin

7

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17 November 2017

Jun-Liang Hou

8

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17 November 2017

Yue-Xiang Chen

9

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17 November 2017

Jun-Ping Zhang

10

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17 November 2017

Xin Zhang

11

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17 November 2017

Wei-Fen Xie

12

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17 November 2017

language of work or name

English

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publication date

1 November 2009

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17 November 2017

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17 November 2017

volume

50

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17 November 2017

issue

5

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17 November 2017

page(s)

1524-1536

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Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

17 November 2017

cites work

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Hepatic lipocytes: the principal collagen-producing cells of normal rat liver

21 January 2018

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Hepatic stellate cells: unique characteristics in cell biology and phenotype

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Transcriptional regulation of hepatic stellate cell activation

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Cellular and molecular mechanisms of fibrosis

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Prominent contribution of portal mesenchymal cells to liver fibrosis in ischemic and obstructive cholestatic injuries.

21 January 2018

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Hepatocyte growth factor attenuates liver fibrosis induced by bile duct ligation

21 January 2018

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Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions

21 January 2018

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Growth factor-induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteins

21 January 2018

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Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells.

21 January 2018

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Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin

21 January 2018

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Pro-fibrogenic potential of PDGF-D in liver fibrosis

21 January 2018

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Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells

21 January 2018

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JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation

21 January 2018

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Differential expression genes analyzed by cDNA array in the regulation of rat hepatic fibrogenesis.

21 January 2018

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Gene silencing by adenovirus-delivered siRNA.

21 January 2018

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

21 January 2018

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Targeted inhibition of platelet-derived growth factor receptor-beta subunit in hepatic stellate cells ameliorates hepatic fibrosis in rats

21 January 2018

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Quantitative ultrasonic tissue characterization as a new tool for continuous monitoring of chronic liver remodelling in mice.

21 January 2018

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Treatment of experimental hepatic fibrosis by combinational delivery of urokinase-type plasminogen activator and hepatocyte growth factor genes

21 January 2018

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Modelling oncogenic Ras/Raf signalling in the mouse.

21 January 2018

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Extracellular signal regulated kinase and SMAD signaling both mediate the angiotensin II driven progression towards overt heart failure in homozygous TGR(mRen2)27.

21 January 2018

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TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways

21 January 2018

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Unc119 regulates myofibroblast differentiation through the activation of Fyn and the p38 MAPK pathway

21 January 2018

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TGFbeta stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signalling

21 January 2018

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Mitogen activated protein kinases in renal fibrosis

21 January 2018

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Role of mechanical and redox stress in activation of mitogen-activated protein kinases in primary cultured rat hepatocytes

21 January 2018

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Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection

21 January 2018

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Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers

21 January 2018

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Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.

21 January 2018

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Complex networks orchestrate epithelial-mesenchymal transitions

21 January 2018

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Epithelial-mesenchymal transitions in tumour progression

21 January 2018

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

21 January 2018

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Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis

21 January 2018

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The epithelial-mesenchymal transition: new insights in signaling, development, and disease

21 January 2018

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ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells.

21 January 2018

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Distinct functions for ERKs?

21 January 2018

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ERK2 but not ERK1 plays a key role in hepatocyte replication: an RNAi-mediated ERK2 knockdown approach in wild-type and ERK1 null hepatocytes.

21 January 2018

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TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21Cip1 or Rb status.

21 January 2018

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Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

21 January 2018

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Off-target effects of siRNA specific for GFP

21 January 2018

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Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting

21 January 2018

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Epithelial-mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease

21 January 2018

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7 January 2021

Signal transduction through MAP kinase cascades

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7 January 2021

Bone morphogenetic protein 4 mediates bile duct ligation induced liver fibrosis through activation of Smad1 and ERK1/2 in rat hepatic stellate cells

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7 January 2021

Enhanced matrix degradation after withdrawal of TGF-beta1 triggers hepatocytes from apoptosis to proliferation and regeneration

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7 January 2021

Identifiers

DOI

10.1002/HEP.23189

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17 November 2017

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