(Q43271986)

18 November 2017

title

Decreased ubiquinone availability and impaired mitochondrial cytochrome oxidase activity associated with statin treatment (English)

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18 November 2017

Andrew J Duncan

1

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18 November 2017

Iain P Hargreaves

2

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18 November 2017

Maxwell S Damian

3

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18 November 2017

John M Land

4

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18 November 2017

Simon J R Heales

5

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18 November 2017

language of work or name

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1 January 2009

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Toxicology Mechanisms and Methods

18 November 2017

published in

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18 November 2017

volume

19

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18 November 2017

issue

1

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18 November 2017

page(s)

44-50

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Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.

18 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Myoglobinuria and COX deficiency in a patient taking cerivastatin and gemfibrozil.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

New advances in lipid-modifying therapies for reducing cardiovascular risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Determination of coenzyme Q10 status in blood mononuclear cells, skeletal muscle, and plasma by HPLC with di-propoxy-coenzyme Q10 as an internal standard.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Biochemical, physiological and medical aspects of ubiquinone function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Saturation kinetics of coenzyme Q in NADH and succinate oxidation in beef heart mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Comparative tolerability of the HMG-CoA reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Lovastatin decreases coenzyme Q levels in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: implications for neuroprotection/neurodegeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

The effect of HMG-CoA reductase inhibitors on coenzyme Q10: possible biochemical/clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Role of P-glycoprotein in statin drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

HMG-CoA reductase inhibitors inhibit inducible nitric oxide synthase gene expression in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Lipophilic statins augment inducible nitric oxide synthase expression in cytokine-stimulated cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Induction of mitochondrial oxidative stress in astrocytes by nitric oxide precedes disruption of energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Treatment of patients with lipid disorders in the primary care setting: new treatment guidelines and their implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

21 January 2018

Over-the-counter statins

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Statin precipitated lactic acidosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Muscle coenzyme Q deficiency in familial mitochondrial encephalomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Statin-associated myopathy with normal creatine kinase levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Pharmacogenomics and pharmacogenetics of cholesterol-lowering therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

The kinetic properties of citrate synthase from rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Comparison of mitochondrial respiratory chain enzyme activities in rodent astrocytes and neurones and a human astrocytoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Lipogenesis from lactate in rat neurons and astrocytes in primary culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: a possible role in statin-induced hepatotoxicity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Statin-associated myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Large-scale chemical dissection of mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

Lovastatin decreases coenzyme Q levels in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15376510802305047

10.1080/15376510802305047

21 January 2018

Identifiers

DOI

1 reference

18 November 2017

1 reference