(Q43276183)

18 November 2017

title

Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attack (English)

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18 November 2017

C Gysemans

1

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18 November 2017

H Callewaert

2

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18 November 2017

F Moore

3

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18 November 2017

M Nelson-Holte

4

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18 November 2017

L Overbergh

5

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18 November 2017

D L Eizirik

6

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18 November 2017

C Mathieu

7

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18 November 2017

publication date

8 September 2009

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18 November 2017

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18 November 2017

volume

52

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18 November 2017

issue

11

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18 November 2017

page(s)

2374-2384

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https://scigraph.springernature.com/pub.10.1007/s00125-009-1514-5

18 November 2017

exact match

0 references

cites work

IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-009-1514-5

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-009-1514-5

Role of cytochrome P-450 arachidonate metabolites in endothelin signaling in rat proximal tubule

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-009-1514-5

Role of interferon regulatory factor-1 in double-stranded RNA-induced iNOS expression by mouse islets

21 January 2018

1 reference

12 December 2020

Complete suppression of insulitis and diabetes in NOD mice lacking interferon regulatory factor-1

1 reference

12 December 2020

Differential roles of Mac-1+ cells, and CD4+ and CD8+ T lymphocytes in primary nonfunction and classic rejection of islet allografts

1 reference

12 December 2020

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

1 reference

12 December 2020

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress

1 reference

12 December 2020

Treatment with an interleukin-1 receptor antagonist protein prolongs mouse islet allograft survival

1 reference

12 December 2020

Human pancreatic islets produce and secrete MCP-1/CCL2: relevance in human islet transplantation

1 reference

12 December 2020

Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production

1 reference

12 December 2020

IL-1 receptor antagonist inhibits recurrence of disease after syngeneic pancreatic islet transplantation to spontaneously diabetic non-obese diabetic (NOD) mice

1 reference

12 December 2020

Perforin and Fas induced by IFNγ and TNFα mediate beta cell death by OT-I CTL

1 reference

12 December 2020

Protective role of IFN-gamma in collagen-induced arthritis conferred by inhibition of mycobacteria-induced granulocyte chemotactic protein-2 production.

1 reference

12 December 2020

Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection

1 reference

12 December 2020

The role of interleukin-1 in the pathogenesis of IDDM.

1 reference

12 December 2020

Convergence of TNFalpha and IFNgamma signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/kappaB promoter element

1 reference

12 December 2020

Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR

1 reference

12 December 2020

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

1 reference

12 December 2020

Dual role of interferon-gamma signalling pathway in sensitivity of pancreatic beta cells to immune destruction

1 reference

12 December 2020

Chemokines and their receptors in islet allograft rejection and as targets for tolerance induction

1 reference

12 December 2020

Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays

1 reference

12 December 2020

Interferon regulatory factor-1 down-regulates cytokine-induced IP-10 expression in pancreatic islets

1 reference

12 December 2020

Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis

1 reference

12 December 2020

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

1 reference

12 December 2020

Prevention of primary non-function of islet xenografts in autoimmune diabetic NOD mice by anti-inflammatory agents

1 reference

12 December 2020

Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells

1 reference

12 December 2020

Molecular mechanisms of iNOS induction by IL-1 beta and IFN-gamma in rat aortic smooth muscle cells

1 reference

12 December 2020

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

1 reference

12 December 2020

Attenuation of nitric oxide synthase induction in IRF-1-deficient glial cells.

1 reference

12 December 2020

Early graft failure of xenogeneic islets in NOD mice is accompanied by high levels of interleukin-1 and low levels of transforming growth factor-beta mRNA in the grafts

1 reference

12 December 2020

A natural interleukin 1 (IL-1) inhibitor counteracts the inhibitory effect of IL-1 on insulin production in cultured rat pancreatic islets

1 reference

12 December 2020

Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells

1 reference

12 December 2020

A critical role for granzyme B, in addition to perforin and TNFalpha, in alloreactive CTL-induced mouse pancreatic beta cell death

1 reference

12 December 2020

A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells

1 reference

12 December 2020

An interleukin-1 receptor antagonist protein protects insulin-producing Beta cells against suppressive effects of interleukin-1?

1 reference

12 December 2020

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

1 reference

12 December 2020

Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo

1 reference

12 December 2020

Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways

1 reference

12 December 2020

The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cells.

1 reference

12 December 2020

Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

1 reference

12 December 2020

Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis

1 reference

12 December 2020

Requirement for transcription factor IRF-1 in NO synthase induction in macrophages.

1 reference

12 December 2020

Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells

1 reference

12 December 2020

Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes

1 reference

12 December 2020

Increased expression of CCL2 in insulin-producing cells of transgenic mice promotes mobilization of myeloid cells from the bone marrow, marked insulitis, and diabetes

1 reference

12 December 2020

Cytotoxic T-Cells From T-Cell Receptor Transgenic NOD8.3 Mice Destroy β-Cells via the Perforin and Fas Pathways

1 reference

12 December 2020

1 reference

12 December 2020

Cloned T cells from a recent onset IDDM patient reactive with insulin B-chain

1 reference

12 December 2020

Interleukin-1beta and inducible form of nitric oxide synthase expression in early syngeneic islet transplantation.

1 reference

12 December 2020

Quantification of chemokines by real-time reverse transcriptase PCR: applications in type 1 diabetes

1 reference

12 December 2020

The use of interleukin-1-receptor antagonists in the treatment of diabetes mellitus

1 reference

12 December 2020

10.1007/S00125-009-1514-5

Identifiers

DOI

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18 November 2017

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