(Q43469385)

23 November 2017

title

PanR1, a dominant negative missense allele of the gene encoding TNF-alpha (Tnf), does not impair lymphoid development (English)

1 reference

23 November 2017

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1

Sophie Rutschmann

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Bruce Beutler

8

object named as

Bruce Beutler

1 reference

23 November 2017

2

Kasper Hoebe

1 reference

23 November 2017

5

Navjiwan Mann

1 reference

23 November 2017

Jonathan Zalevsky

3

1 reference

23 November 2017

Xin Du

4

1 reference

23 November 2017

Bassil I Dahiyat

6

1 reference

23 November 2017

Paul Steed

7

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23 November 2017

language of work or name

English

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publication date

1 June 2006

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23 November 2017

published in

Journal of Immunology

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23 November 2017

volume

176

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23 November 2017

issue

12

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23 November 2017

page(s)

7525-7532

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Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor.

23 November 2017

cites work

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Organogenesis of lymphoid tissues

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Signaling for survival and apoptosis in the immune system

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Characterization of tumor necrosis factor-deficient mice

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Novel tumor necrosis factor-knockout mice that lack Peyer's patches

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Noncleavable transmembrane mouse tumor necrosis factor-alpha (TNFalpha) mediates effects distinct from those of wild-type TNFalpha in vitro and in vivo

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Activators and target genes of Rel/NF-kappaB transcription factors

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

TNFRSF1A mutations and autoinflammatory syndromes

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Development and maturation of secondary lymphoid tissues.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Development of anti-TNF therapy for rheumatoid arthritis

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

The structure of mouse tumour-necrosis factor at 1.4 Å resolution: towards modulation of its selectivity and trimerization

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Structure of tumour necrosis factor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

The biology of cachectin/TNF--a primary mediator of the host response

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Transmembrane TNF induces an efficient cell-mediated immunity and resistance to Mycobacterium bovis bacillus Calmette-Guérin infection in the absence of secreted TNF and lymphotoxin-alpha.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Independent protective effects for tumor necrosis factor and lymphotoxin alpha in the host response to Listeria monocytogenes infection.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Mutational analysis of structure--activity relationships in human tumor necrosis factor-alpha.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

The resistance against Listeria monocytogenes and the formation of germinal centers depend on a functional death domain of the 55 kDa tumor necrosis factor receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

The TNF and TNF receptor superfamilies: integrating mammalian biology

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Resistance and susceptibility of mice to bacterial infection: genetics of listeriosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

The role of lymphotoxin in development and maintenance of secondary lymphoid tissues

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

A tumor necrosis factor (TNF) receptor-IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

TNF-R1 signaling: a beautiful pathway

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Role of hemolysin for the intracellular growth of Listeria monocytogenes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Inactivation of TNF signaling by rationally designed dominant-negative TNF variants

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

A comparison between two methods for measuring tumor necrosis factor in biological fluids

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Exclusive expression of transmembrane TNF-alpha in mice reduces the inflammatory response in early lipid lesions of aortic sinus

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.176.12.7525

Identifiers

DOI

10.4049/JIMMUNOL.176.12.7525

1 reference

23 November 2017

1 reference