(Q43471124)

23 November 2017

Dependence of fertility on kisspeptin-Gpr54 signaling at the GnRH neuron (English)

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23 November 2017

8

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23 November 2017

Xinhuai Liu

3

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Juan Roa

object named as

Juan Roa

4

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Jenny Clarkson

object named as

Jenny Clarkson

2

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author name string

Milen Kirilov

1

1 reference

23 November 2017

Pauline Campos

5

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23 November 2017

Rob Porteous

6

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23 November 2017

Günther Schütz

7

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23 November 2017

language of work or name

English

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publication date

1 January 2013

1 reference

23 November 2017

Nature Communications

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23 November 2017

4

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23 November 2017

2492

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https://scigraph.springernature.com/pub.10.1038/ncomms3492

23 November 2017

0 references

cites work

The GPR54 gene as a regulator of puberty

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

The role of kisspeptins and GPR54 in the neuroendocrine regulation of reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin signaling in the brain: recent developments and future challenges.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Hypothalamic control of the pituitary-gonadal axis in higher primates: key advances over the last two decades

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptins and GnRH neuronal signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin and the hypothalamic control of reproduction: lessons from the human

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptins and the placenta: regulation of trophoblast invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

KiSS-1 and GPR54 at the pituitary level: overview and recent insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin regulates gonadotroph and somatotroph function in nonhuman primate pituitary via common and distinct signaling mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Evidence for a celiac ganglion-ovarian kisspeptin neural network in the rat: intraovarian anti-kisspeptin delays vaginal opening and alters estrous cyclicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Gpr54-/- mice show more pronounced defects in spermatogenesis than Kiss1-/- mice and improved spermatogenesis with age when exposed to dietary phytoestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin increases gamma-aminobutyric acidergic and glutamatergic transmission directly to gonadotropin-releasing hormone neurons in an estradiol-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin directly excites anorexigenic proopiomelanocortin neurons but inhibits orexigenic neuropeptide Y cells by an indirect synaptic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin-GPR54 signaling in mouse NO-synthesizing neurons participates in the hypothalamic control of ovulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Distribution and postnatal development of Gpr54 gene expression in mouse brain and gonadotropin-releasing hormone neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Female reproductive maturation in the absence of kisspeptin/GPR54 signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin depolarizes gonadotropin-releasing hormone neurons through activation of TRPC-like cationic channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin excites gonadotropin-releasing hormone neurons through a phospholipase C/calcium-dependent pathway regulating multiple ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Olfactory inputs to hypothalamic neurons controlling reproduction and fertility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Definition of estrogen receptor pathway critical for estrogen positive feedback to gonadotropin-releasing hormone neurons and fertility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

KiSS1 metastasis suppressor gene product induces suppression of tyrosine kinase receptor signaling to Akt, tumor necrosis factor family ligand expression, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Temporal and spatial regulation of CRE recombinase expression in gonadotrophin-releasing hormone neurones in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Immunohistochemical localization of GnRH and RFamide-related peptide-3 in the ovaries of mice during the estrous cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin/Gpr54-independent gonadotrophin-releasing hormone activity in Kiss1 and Gpr54 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Redundancy in Kiss1 expression safeguards reproduction in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Gonadotropin-releasing hormone neuron requirements for puberty, ovulation, and fertility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Implantation of normal fetal preoptic area into hypogonadal mutant mice: temporal relationships of the growth of gonadotropin-releasing hormone neurons and the development of the pituitary/testicular axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

A CamKIIalpha iCre BAC allows brain-specific gene inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Gap junctions between neuronal inputs but not gonadotropin-releasing hormone neurons control estrous cycles in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Frequency-dependent recruitment of fast amino acid and slow neuropeptide neurotransmitter release controls gonadotropin-releasing hormone neuron excitability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Leptin inhibits testosterone secretion from adult rat testis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

Kisspeptin Activation of Gonadotropin Releasing Hormone Neurons and Regulation of KiSS-1 mRNA in the Male Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

GABA- and glutamate-activated channels in green fluorescent protein-tagged gonadotropin-releasing hormone neurons in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

7 January 2021

Differential gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acid expression patterns in different tissues of the female rat across the estrous cycle

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

7 January 2021

Transgenic mouse models to study Gpr54/kisspeptin physiology

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

7 January 2021

Combined retrograde tracing and immunocytochemical identification of luteinizing hormone-releasing hormone- and somatostatin-containing neurons projecting to the median eminence of the rat

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3492

7 January 2021

Identifiers

DOI

10.1038/NCOMMS3492

1 reference

23 November 2017

0 references

1 reference