(Q43479791)

English

Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses

scientific article published in July 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 November 2017

Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 November 2017

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Foo Y Liew

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Europe PubMed Central

PubMed publication ID

23 November 2017

author name string

Helen S Goodridge

1

1 reference

Europe PubMed Central

PubMed publication ID

23 November 2017

William Harnett

2

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Europe PubMed Central

PubMed publication ID

23 November 2017

Margaret M Harnett

4

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Europe PubMed Central

PubMed publication ID

23 November 2017

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publication date

1 July 2003

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Europe PubMed Central

PubMed publication ID

23 November 2017

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Europe PubMed Central

PubMed publication ID

23 November 2017

109

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Europe PubMed Central

PubMed publication ID

23 November 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

23 November 2017

415-425

1 reference

Europe PubMed Central

PubMed publication ID

23 November 2017

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

1 reference

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The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

1 reference

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27 August 2018

Regulation of interleukin-12 production in antigen-presenting cells

1 reference

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Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

1 reference

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27 August 2018

The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species

1 reference

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27 August 2018

Phosphoinositide 3-kinase signalling pathways

1 reference

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TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide.

1 reference

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27 August 2018

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

1 reference

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27 August 2018

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

1 reference

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JNK1 is required for T cell-mediated immunity against Leishmania major infection.

1 reference

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27 August 2018

An IFN-gamma-inducible transcription factor, IFN consensus sequence binding protein (ICSBP), stimulates IL-12 p40 expression in macrophages

1 reference

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27 August 2018

Protein kinases: six degrees of separation?

1 reference

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27 August 2018

Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subver

1 reference

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27 August 2018

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10.

1 reference

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Pasteurella haemolytica A1-derived leukotoxin and endotoxin induce intracellular calcium elevation in bovine alveolar macrophages by different signaling pathways

1 reference

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27 August 2018

SHIP modulates immune receptor responses by regulating membrane association of Btk.

1 reference

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27 August 2018

Synergistic regulation of the human interleukin-12 p40 promoter by NFkappaB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

Co-receptor and accessory regulation of B-cell antigen receptor signal transduction.

1 reference

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27 August 2018

Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

Immunomodulatory functions and molecular regulation of IL-12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: evidence of functional synergy between C/EBP and Rel proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

Selective suppression of interleukin-12 induction after macrophage receptor ligation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

Phosphoinositide kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

Structure and chromosomal location of the mouse interleukin-12 p35 and p40 subunit genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

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Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

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27 August 2018

Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist

1 reference

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Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events

1 reference

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Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase

1 reference

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Regulation of interleukin 12 p40 expression through an NF-kappa B half-site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782981

27 August 2018

Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity

1 reference

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Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.

1 reference

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Homology of the p40 subunit of natural killer cell stimulatory factor (NKSF) with the extracellular domain of the interleukin-6 receptor

1 reference

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Stimulus-response coupling in monocytes infected with Leishmania. Attenuation of calcium transients is related to defective agonist-induced accumulation of inositol phosphates

1 reference

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Cloning and expression of murine IL-12

1 reference

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1 reference

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Bacterial lipopolysaccharide induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in macrophages

1 reference

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IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

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inferred from PubMed ID database lookup

Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disparate intracellular processing of human IL-12 preprotein subunits: atypical processing of the P35 signal peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD19 signal transduction in normal human B cells: linkage to downstream pathways requires phosphatidylinositol 3-kinase, protein kinase C and Ca2+

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum IL-12 in systemic lupus erythematosus: absence of p70 heterodimers but presence of p40 monomers correlating with disease activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3K-mediated negative feedback regulation of IL-12 production in DCs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of IFN regulatory factor-1 binding site in IL-12 p40 gene promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence similarity between NKSF and the IL-6/G-CSF family

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of murine B cell proliferation and down-regulation of protein kinase C levels by a phosphorylcholine-containing filarial excretory-secretory product

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wortmannin, a specific inhibitor of phosphatidylinositol-3-kinase, enhances LPS-induced NO production from murine peritoneal macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taurine blunts LPS-induced increases in intracellular calcium and TNF-alpha production by Kupffer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of murine IL-12 is regulated by translational control of the p35 subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Examination of the signal transduction pathways leading to activation of extracellular signal-regulated kinase by formyl-methionyl-leucyl-phenylalanine in rat neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12807488

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2567.2003.01689.X

1 reference

Europe PubMed Central

PubMed publication ID

23 November 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 November 2017

ResearchGate publication ID

0 references

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