(Q43483568)

23 November 2017

title

The nonimmunoglobulin portion of lambda5 mediates cell-autonomous pre-B cell receptor signaling (English)

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23 November 2017

Kazuo Ohnishi

1

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23 November 2017

Fritz Melchers

series ordinal

2

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23 November 2017

language of work or name

English

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publication date

3 August 2003

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23 November 2017

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23 November 2017

volume

4

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23 November 2017

issue

9

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23 November 2017

page(s)

849-856

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Fit for life in the immune system? Surrogate L chain tests H chains that test L chains

23 November 2017

cites work

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The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain

21 January 2018

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The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface

21 January 2018

1 reference

The surrogate light chain in B-cell development.

21 January 2018

1 reference

The human pre-B cell receptor: structural constraints for a tentative model of the pseudo-light (psi L) chain.

21 January 2018

1 reference

Novel mechanisms control the folding and assembly of lambda5/14.1 and VpreB to produce an intact surrogate light chain

21 January 2018

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The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion.

21 January 2018

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The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells

21 January 2018

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A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

21 January 2018

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A critical role of λ5 protein in B cell development

21 January 2018

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Loss of precursor B cell expansion but not allelic exclusion in VpreB1/VpreB2 double-deficient mice

21 January 2018

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B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta

21 January 2018

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Precursor B cell receptor-dependent B cell proliferation and differentiation does not require the bone marrow or fetal liver environment

21 January 2018

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Surrogate light chain-mediated interaction of a soluble pre-B cell receptor with adherent cell lines

21 January 2018

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Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex

21 January 2018

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Precursor B cells of mouse bone marrow express two different complexes with the surrogate light chain on the surface

21 January 2018

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The variable, C(H)1, C(H)2 and C(H)3 domains of Ig heavy chain are dispensable for pre-BCR function in transgenic mice.

21 January 2018

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A complex of glycoproteins is associated with VpreB/lambda 5 surrogate light chain on the surface of mu heavy chain-negative early precursor B cell lines

21 January 2018

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Expression of surrogate light chain receptors is restricted to a late stage in pre-B cell differentiation

21 January 2018

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Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides.

21 January 2018

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A B cell superantigen-induced persistent "Hole" in the B-1 repertoire

21 January 2018

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A novel mechanism for B cell repertoire maturation based on response by B cell precursors to pre-B receptor assembly.

21 January 2018

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Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene loci

21 January 2018

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

21 January 2018

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Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanism

21 January 2018

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VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus

21 January 2018

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7 January 2021

The B cell receptor, but not the pre-B cell receptor, mediates arrest of B cell differentiation

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7 January 2021

The expression of Vpre-B/lambda 5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice

1 reference

7 January 2021

Monoclonal antibodies specific for murine IgM I. Characterization of antigenic determinants on the four constant domains of the μ heavy chain

1 reference

7 January 2021

Changes in the V(H) gene repertoire of developing precursor B lymphocytes in mouse bone marrow mediated by the pre-B cell receptor

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7 January 2021

A temperature-sensitive mutant of Abelson murine leukemia virus confers inducibility of IgM expression to transformed lymphoid cells.

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7 January 2021

Endocytosis of beta 2 integrins by stimulated human neutrophils analyzed by flow cytometry

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7 January 2021

Identifiers

DOI

10.1038/NI959

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23 November 2017

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