(Q43507480)

20 February 2018

title

Genome-wide association study identifies MAPT locus influencing human plasma tau levels (English)

1 reference

20 February 2018

genome-wide association study

main subject

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author

Alzheimer's Disease Neuroimaging Initiative

14

Alzheimer's Disease Neuroimaging Initiative

1 reference

20 February 2018

Jin-Tai Yu

2

0 references

Henrik Zetterberg

5

Henrik Zetterberg

1 reference

20 February 2018

8

Michael W Weiner

1 reference

20 February 2018

6

Kaj Blennow

1 reference

20 February 2018

11

Bruce L Miller

1 reference

20 February 2018

13

Adam L Boxer

1 reference

20 February 2018

Joel H Kramer

9

Joel H Kramer

1 reference

20 February 2018

Howard J Rosen

10

Howard Rosen

1 reference

20 February 2018

Giovanni Coppola

12

Giovanni Coppola

1 reference

20 February 2018

Jennifer S Yokoyama

7

Jennifer S Yokoyama

1 reference

20 February 2018

Kevin J Wojta

3

Kevin Wojta

1 reference

20 February 2018

author name string

Jason Chen

1

1 reference

20 February 2018

Hui-Fu Wang

4

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20 February 2018

language of work or name

English

0 references

publication date

18 January 2017

1 reference

20 February 2018

published in

Neurology

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20 February 2018

volume

88

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20 February 2018

page(s)

669-676

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20 February 2018

issue

7

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20 February 2018

describes a project that uses

genome-wide association study

1 reference

based on heuristic

inferred from title

cites work

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

25 May 2018

1 reference

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Second-generation PLINK: rising to the challenge of larger and richer datasets

25 May 2018

1 reference

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Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Biomarker modeling of Alzheimer's disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Variation in tau isoform expression in different brain regions and disease states

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort

25 May 2018

1 reference

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LocusZoom: regional visualization of genome-wide association scan results

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Evolutionary toggling of the MAPT 17q21.31 inversion region

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Risk alleles for multiple sclerosis identified by a genomewide study

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Haplotype-specific expression of exon 10 at the human MAPT locus

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Epidemiological, clinical, and genetic characteristics of early-onset parkinsonism

25 May 2018

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Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Neurodegenerative tauopathies

25 May 2018

1 reference

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Association between early-onset Parkinson's disease and mutations in the parkin gene

25 May 2018

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25 May 2018

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Peripheral Total Tau in Military Personnel Who Sustain Traumatic Brain Injuries During Deployment.

25 May 2018

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Parkin polymorphisms in progressive supranuclear palsy

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Genetic variation at the tau locus and clinical syndromes associated with progressive supranuclear palsy.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

The structure of the tau haplotype in controls and in progressive supranuclear palsy.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Total tau and phosphorylated tau 181 levels in the cerebrospinal fluid of patients with frontotemporal dementia due to P301L and G272V tau mutations.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Tau exon 10 +16 mutation FTDP-17 presenting clinically as sporadic young onset PSP.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Steele-Richardson-Olszewski syndrome in a patient with a single C212Y mutation in the parkin protein.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Association of an extended haplotype in the tau gene with progressive supranuclear palsy.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Genetic evidence for the involvement of tau in progressive supranuclear palsy

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

High-density SNP haplotyping suggests altered regulation of tau gene expression in progressive supranuclear palsy

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317386

Fine mapping of the MAPT locus using quantitative trait analysis identifies possible causal variants in Alzheimer's disease

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28100725

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1212/WNL.0000000000003615

1 reference

20 February 2018

PMCID

5317386

1 reference

20 February 2018

PubMed ID

28100725

1 reference

20 February 2018